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Annals of Intensive Care
Fig. 4 | Annals of Intensive Care

Fig. 4

From: The clinical efficacy of intravenous IgM-enriched immunoglobulin (pentaglobin) in sepsis or septic shock: a meta-analysis with trial sequential analysis

Fig. 4

Random-effects meta-regression analyses showing the relationship between the study effect size and a publication year, b number of participating centers, and mortality rates of the IVIgGM and control groups. c Number of patients, d mean age, e duration of treatment, f daily dose, h total dose, i mortality rates of the IVIgGM, j mortality rates of the control groups. The size of the circles is inversely proportional to the size of the result study variance, so that more precise studies have larger circles

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