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Annals of Intensive Care

Table 2 Univariate logistic regression analysis for the association with ICU and hospital mortality in all included patients (n = 3966)

From: The association of intravenous insulin and glucose infusion with intensive care unit and hospital mortality: a retrospective study

Variable

ICU mortality (n = 309)

Hospital mortality (n = 455)

OR (95% CI)

p value

OR (95% CI)

p value

Age (per 10 years)

1.14 (1.04, 1.25)

0.006

1.26 (1.16, 1.36)

< 0.001

Gender (male as reference)

1.19 (0.94, 1.51)

0.148

1.15 (0.94, 1.41)

0.172

BMI (per kg/m2)

1.01 (0.99, 1.03)

0.438

1.00 (0.98, 1.01)

0.577

History of diabetes

1.19 (0.91, 1.57)

0.203

1.27 (1.01, 1.60)

0.039

History of insulin use

1.55 (1.09, 2.22)

0.015

1.50 (1.10, 2.04)

0.010

History of liver cirrhosis

2.46 (1.27, 4.76)

0.007

3.81 (2.25, 6.47)

< 0.001

Cardiothoracic surgery patients

0.22 (0.16, 0.30)

< 0.001

0.16 (0.12, 0.21)

< 0.001

APACHE IV PM (per %)

1.04 (1.04, 1.05)

< 0.001

1.04 (1.04, 1.05)

< 0.001

Maximum SOFA score (per point)

1.50 (1.45, 1.56)

< 0.001

1.41 (1.36, 1.45)

< 0.001

Corticosteroids during admission

3.88 (2.67, 5.63)

< 0.001

3.28 (2.46, 4.38)

< 0.001

Average sodium > 145 mmol/L

3.26 (2.25, 4.74)

< 0.001

3.53 (2.55, 4.89)

< 0.001

Total parenteral feeding

0.79 (0.47, 1.33)

0.370

0.80 (0.49, 1.30)

0.359

Daily intake (all sources, per 100 kcal)

1.02 (1.01, 1.03)

< 0.001

1.03 (1.02, 1.03)

< 0.001

Length of ICU stay (per day)

1.04 (1.03, 1.05)

< 0.001

1.04 (1.03, 1.05)

< 0.001

Mean BG (per mmol/L)

0.80 (0.72, 0.89)

< 0.001

0.81 (0.75, 0.88)

< 0.001

MAG change (per mmol/L/h)

1.48 (1.03, 2.11)

0.034

1.32 (0.97, 1.80)

0.083

Percentage BG < 4.4 mmol/L (per %)

1.07 (1.05, 1.09)

< 0.001

1.07 (1.05, 1.09)

< 0.001

Percentage BG > 11.1 mmol/L (per %)

1.00 (0.99, 1.01)

0.649

1.00 (0.99, 1.01)

0.613

Incidence glucose < 2.2 mmol/L

4.81 (1.85, 12.48)

0.001

3.11 (1.20, 8.07)

0.019

Incidence glucose < 4.4 mmol/L

3.88 (3.04, 4.97)

< 0.001

3.51 (2.83, 4.34)

< 0.001

IV insulin per kg per day (per 0.1 IU)

1.10 (1.07, 1.12)

< 0.001

1.10 (1.08, 1.12)

< 0.001

IV glucose per day (per g increase)

1.01 (1.01, 1.02)

< 0.001

1.01 (1.01, 1.02)

< 0.001

Fluid balance (per L increase)

1.22 (1.19, 1.24)

< 0.001

1.17 (1.15, 1.19)

< 0.001

  1. For categorical variables, no was used as reference category
  2. APACHE Acute Physiology and Chronic Health Evaluation, BG blood glucose, BMI body mass index, CI confidence interval, ICU intensive care unit, IU international unit, IV intravenous, MAG mean absolute glucose, OR odds ratio
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