Chest CT scan and alveolar procollagen III to predict lung fibroproliferation in acute respiratory distress syndrome

Annals of Intensive Care

Table 1 Characteristics of the patients at ARDS onset

Variables	All patients (n = 192)
Age (years)	60 [48–69]
Sex [n (%) men]	137 (71.4)
Body mass index (kg/m²)	25.8 [21.9–29.2]
SAPS II	47 [38–69]
SOFA	8 [7–11]
Cause of ARDS [n (%)]
Pneumonia	104 (54.2)
Aspiration	28 (14.6)
Extra-pulmonary sepsis	28 (14.6)
Others^a	32 (16.6)
Minute ventilation (L/min)	9.3 [6.6–10.8]
Tidal volume (mL/kg PBW)	6.1 [5.0–6.7]
Respiratory rate (cycle/min)	24 [18–27]
Plateau pressure (cmH₂O)	25 [21–28]
Driving pressure (cmH₂O)	13 [9–16]
Total PEEP (cmH₂O)	10 [8–13]
Respiratory system compliance (mL/cmH₂O)	26.5 [21.3–36.6]
pH	7.36 [7.29–7.43]
PaO₂/FiO₂ (mmHg)	129 [92–197]
PaCO₂ (mmHg)	43 [36–50]
Ventilator-free days at day 60 (days)	22 [0–46]
Length of ICU stay (days)	24 [12–38]
ICU mortality [n (%)]	69 (35.7)

Values are expressed as median [IQR], except for sex, cause of ARDS and ICU mortality [n (%)]
ARDS acute respiratory distress syndrome, SAPS II simplified acute physiologic score, SOFA sequential organ failure assessment, PBW predicted body weight, PEEP positive end-expiratory pressure, ICU intensive care unit
^aChest trauma with lung contusion (n = 18), transfusion-related acute lung injury (n = 10), hemoptysis (n = 4)