Table 2 Clinical and biological data at Day 1
From: Risk factors for progression toward brain death after out-of-hospital cardiac arrest
All patients (n = 214) | No brain death (n = 172) | Brain death (n = 42) | p | |
|---|---|---|---|---|
Hemodynamics | ||||
MAP, mmHg | 78 (65–91) | 80 (65–92) | 73 (63–82) | 0.09 |
Heart rate, bpm | 100 (85–114) | 98 (82–112) | 110 (95–119) | < 0.01 |
Vasoactive drugs | 107 (50) | 74 (43) | 33 (79) | < 0.01 |
Temperature | ||||
Temperature, °C | 37.4 (36.2–38.2) | 37.5 (36.4–38.1) | 37.5 (36.1–38.7) | 0.80 |
TTM | 102 (48) | 81 (47) | 21 (50) | 0.86 |
Continuous sedation | 88 (41) | 75 (44) | 13 (31) | 0.16 |
Neurological examination | ||||
GCS score | 3 (3–4) | 3 (3–5) | 3 (3–3) | < 0.001 |
GCS Motor subscore ≤ 2 | 181 (85) | 139 (81) | 42 (100) | < 0.001 |
Myoclonus | 68 (32) | 67 (39) | 1 (2) | < 0.001 |
Pupillary light reflex present | 112 (52) | 110 (64) | 2 (5) | < 0.001 |
Spontaneous ventilation absent | 75 (35) | 45 (26) | 30 (71) | < 0.001 |
Biological variables | ||||
Arterial pH | 7.25 (7.14–7.32) | 7.25 (7.15–7.33) | 7.17 (7.07–7.29) | 0.02 |
PaCO2, KPa | 5.3 (4.5–6.5) | 5.3 (4.6–6.5) | 5.4 (4.4–7.0) | 0.97 |
Serum lactate, mmol/l | 7.7 (4.9–11.0) | 7.4 (4.5–10.7) | 8.9 (5.8–12.0) | 0.07 |
Troponin, µg/l | 0.7 (0.1–5.1) | 0.5 (0.1–3.6) | 1,9 (0.3–19.0) | < 0.01 |
ALT, IU/L | 104 (44–261) | 84 (39–206) | 178 (92–376) | < 0.001 |
Creatinine, µmol/l | 110 (81–173) | 107 (80–172) | 124 (87–178) | 0.33 |
Platelets, 109/l | 201 (155–256) | 208 (157–261) | 181 (144–242) | 0.29 |
SOFA score | 9 (6–12) | 9 (6–11) | 11 (9–14) | < 0.001 |
SAPS II | 74 (65–86) | 75 (64–86) | 74 (69–86) | 0.91 |