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Table 2 Clinical and biological data at Day 1

From: Risk factors for progression toward brain death after out-of-hospital cardiac arrest

  All patients (n = 214) No brain death (n = 172) Brain death (n = 42) p
Hemodynamics
 MAP, mmHg 78 (65–91) 80 (65–92) 73 (63–82) 0.09
 Heart rate, bpm 100 (85–114) 98 (82–112) 110 (95–119) < 0.01
 Vasoactive drugs 107 (50) 74 (43) 33 (79) < 0.01
Temperature     
 Temperature, °C 37.4 (36.2–38.2) 37.5 (36.4–38.1) 37.5 (36.1–38.7) 0.80
 TTM 102 (48) 81 (47) 21 (50) 0.86
Continuous sedation 88 (41) 75 (44) 13 (31) 0.16
Neurological examination     
 GCS score 3 (3–4) 3 (3–5) 3 (3–3) < 0.001
 GCS Motor subscore ≤ 2 181 (85) 139 (81) 42 (100) < 0.001
 Myoclonus 68 (32) 67 (39) 1 (2) < 0.001
 Pupillary light reflex present 112 (52) 110 (64) 2 (5) < 0.001
 Spontaneous ventilation absent 75 (35) 45 (26) 30 (71) < 0.001
Biological variables
 Arterial pH 7.25 (7.14–7.32) 7.25 (7.15–7.33) 7.17 (7.07–7.29) 0.02
 PaCO2, KPa 5.3 (4.5–6.5) 5.3 (4.6–6.5) 5.4 (4.4–7.0) 0.97
 Serum lactate, mmol/l 7.7 (4.9–11.0) 7.4 (4.5–10.7) 8.9 (5.8–12.0) 0.07
 Troponin, µg/l 0.7 (0.1–5.1) 0.5 (0.1–3.6) 1,9 (0.3–19.0) < 0.01
 ALT, IU/L 104 (44–261) 84 (39–206) 178 (92–376) < 0.001
 Creatinine, µmol/l 110 (81–173) 107 (80–172) 124 (87–178) 0.33
 Platelets, 109/l 201 (155–256) 208 (157–261) 181 (144–242) 0.29
SOFA score 9 (6–12) 9 (6–11) 11 (9–14) < 0.001
SAPS II 74 (65–86) 75 (64–86) 74 (69–86) 0.91
  1. Data are expressed as median (interquartile range) or number (%)
  2. MAP mean arterial pressure, TTM targeted temperature management, GCS Glasgow Coma Scale, PaCO2 arterial partial pressure of carbon dioxide, ALT alanine aminotransferase, SOFA Sequential Organ Failure Assessment, SAPS II Simplified Acute Physiology Score II