|
Fixed effects
|
Estimate
|
95% confidence interval
|
p value
|
|---|
|
Global cardiac function
|
|
Ees (mmHg ml−1)
|
44.89
|
34.28 to 55.49
|
< 0.001
|
|
Ea (mmHg ml−1)
|
− 29.47
|
− 33.26 to − 25.68
|
< 0.001
|
|
LV EDV (ml)
|
− 0.12
|
− 0.15 to − 0.08
|
< 0.001
|
|
Heart rate (bpm)
|
0.17
|
0.05 to 0.29
|
0.006
|
|
Diastolic function
|
|
LV β constant (a.u.)
|
1340.3
|
474.9 to 1932.6
|
< 0.001
|
|
τ (ms)
|
− 1.28
|
− 1.49 to − 1.07
|
< 0.001
|
|
VAC (Ea/Ees) (a.u.)
|
− 10.6
|
− 11.85 to − 9.37
|
< 0.001
|
|
LV mechanical efficiency (%)
|
0.87
|
0.85 to 0.90
|
< 0.001
|
- Estimate reflects the average change in the LVEF per unit increase of each fixed effect
- Ees left ventricular end-systolic elastance; Ea effective arterial elastance, LV left ventricle, EDV end-diastolic volume, EDPVR slope of the end-diastolic pressure–volume relationship, β LV chamber stiffness constant obtained from the end-diastolic pressure-volume relationship, τ (tau) time constant of the isovolumetric LV pressure relaxation, VAC ventriculo-arterial coupling
