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Table 3 Estimated values of different variables on left ventricular ejection fraction (LVEF) according to a linear mixed-effects model analysis

From: Determinants of left ventricular ejection fraction and a novel method to improve its assessment of myocardial contractility

Fixed effects Estimate 95% confidence interval p value
Global cardiac function
 Ees (mmHg ml−1) 44.89 34.28 to 55.49 < 0.001
 Ea (mmHg ml−1) − 29.47 − 33.26 to − 25.68 < 0.001
 LV EDV (ml) − 0.12 − 0.15 to − 0.08 < 0.001
 Heart rate (bpm) 0.17 0.05 to 0.29 0.006
Diastolic function
 LV β constant (a.u.) 1340.3 474.9 to 1932.6 < 0.001
 τ (ms) − 1.28 − 1.49 to − 1.07 < 0.001
VAC (Ea/Ees) (a.u.) − 10.6 − 11.85 to − 9.37 < 0.001
LV mechanical efficiency (%) 0.87 0.85 to 0.90 < 0.001
  1. Estimate reflects the average change in the LVEF per unit increase of each fixed effect
  2. Ees left ventricular end-systolic elastance; Ea effective arterial elastance, LV left ventricle, EDV end-diastolic volume, EDPVR slope of the end-diastolic pressure–volume relationship, β LV chamber stiffness constant obtained from the end-diastolic pressure-volume relationship, τ (tau) time constant of the isovolumetric LV pressure relaxation, VAC ventriculo-arterial coupling