Association between post-procedural hyperoxia and poor functional outcome after mechanical thrombectomy for ischemic stroke: an observational study

Annals of Intensive Care

Table 2 Confounding variables included in the regression model

Characteristic	mRS < 4 N = 169	mRS ≥ 4 N = 164	Significance level (p value)
Age in years	67 (55–76)	74 (66–79)	< 0.01
Male sex	84 (49.7)	78 (47.6)	0.70
History of smoking	57 (33.7)	40 (24.4)	0.06
Baseline Rankin			0.02
0	130 (76.9)	107 (65.6)	0.02
1	27 (16.0)	36 (22.1)	0.16
≥ 2	12 (7.1)	20 (12.3)	0.11
Hypertension	104 (61.5)	121 (73.8)	0.02
Diabetes mellitus	40 (23.7)	55 (33.5)	0.05
History of COPD	10 (5.9)	16 (9.8)	0.19
History of CRF^a	7 (4.1)	12 (7.3)	0.21
Previous anticoagulation therapy	22 (13.0)	31 (18.9)	0.14
Preprocedure GCS	15 (14–15)	14 (11–15)	< 0.01
Preprocedure NIHSS	16 (11–20)	19 (16–22)	< 0.01
APACHE	13 (12–17)	18 (14–24)	< 0.01
Findings in TC			0.12
Without ischemia	74 (44.3)	59 (36.4)	0.14
Acute ischemic areas^b	73 (43.7)	89 (54.9)	0.04
Areas of ancient stroke	20 (12.0)	14 (8.6)	0.32
Mismatch	70 (60–80)	60 (40–80)	< 0.01
Wake-up stroke	14 (8.3)	23 (14.0)	0.10
Time (min.) onset of symptoms to IAMT	270 (210–360)	290 (211–390)	0.17
Reperfusion degree^c			< 0.01
Successful reperfusion	164 (97.0)	144 (87.8)
Non-successful reperfusion	5 (3.0)	20 (12.2)
OTI at admission^d	71 (42.0)	105 (64.0)	< 0.01

This table value of quantitative variables expressed as median and interquartile range. Values of qualitative variables expressed as n (%)
^aCreatinine clearance < 60 ml/min/1.73 m²
^bIncluded signs of acute ischemia and indirect signs of ischemia: hyperdense middle cerebral artery sign, hemispheric sulcus and/or insular cortex effacement, contrast attenuation, ventricular compression
^cSuccessful reperfusion included TICI 2b and TICI 3. Non-successful reperfusion includes TICI ≤ 2a
^dPatients intubated at ICU admission after IAMT