Table 2 Primary and Secondary Outcomes in the VERROU-REA Study (N = 396)

Overall duration of the first catheter (days), median (Q1, Q3)^a

7 (3, 10)

5 (3, 11)

0.51

First hemodialysis non-tunneled catheter-days, n

1461

1590

Fibrinolysis for the first non-tunneled hemodialysis catheter, n (%)

2 (1%)

0

1

 Incidence rate per 1000 catheter-days

1.37

0

Bleeding at the insertion site of the catheter, n (%)

1 (1%)

5 (3%)

0.12

 Incidence rate per 1000 catheter-days

0.68

3.14

Hematoma at the insertion site of the first catheter, n (%)

3 (2%)

1 (1%)

0.62

 Incidence rate per 1000 catheter-days

2.05

0.63

Thrombosis of the first non-tunneled hemodialysis catheter, n (%)

9 (5%)

3 (2%)

0.14

 Incidence rate per 1000 catheter-days

6.16

1.89

Local first catheter-related infection, n (%)

7 (14%)

8 (19%)

0.55

 Incidence rate per 1000 catheter-days

4.79

5.03

General first catheter-related infection, n (%)

4 (8%)

1 (2%)

0.37

 Incidence rate per 1000 catheter-days

2.74

0.63

First catheter-related bloodstream infection, n (%)

1 (2%)

0

1

 Incidence rate per 1000 catheter-days

0.68

0

Heparin-induced thrombocytopenia

4 (2%)

2 (1%)

1

Bleeding events during follow-up

41 (21%)

37 (19%)

0.65

 Requiring transfusion packs red blood cells

22 (11%)

27 (14%)

0.42

 Requiring transfusion of ≥ 2 packs red blood cells

20 (10%)

26 (13%)

0.33

Death at 28 days, n (%)

88 (44%)

94 (48%)

0.49

Death in ICU, n (%)

84 (42%)

92 (47%)

0.37

Length of ICU stay (from randomization) (days), median (Q1, Q3)

6 (3, 14)

6 (3, 12)

0.70

In-hospital death, n (%)

102 (51%)

108 (55%)

0.48

Length of hospital stay (from randomization) (days), median (Q1, Q3)

15 (6, 31)

12 (4, 27)

0.18