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Table 2 Treatment according to the type of diabetes

From: Initial management of diabetic ketoacidosis and prognosis according to diabetes type: a French multicentre observational retrospective study

Type of treatment

N

Total (n = 122)

Type 1 diabetes (n = 60)

Type 2 or secondary diabetes (n = 28)

Newly diagnosed diabetes (n = 34)

p value

Vascular filling solution on D1

 Normal saline (0.9% NaCl)

112

112 (100)

54 (100)

25 (100)

33 (100)

 

 1.4% sodium bicarbonate

108

6 (5.6)

4 (7.8)

1 (4)

1 (3.1)

0.865

 4.2% or 8.4% sodium bicarbonate

108

7 (6.5)

3 (5.9)

3 (12)

1 (3.1)

0.464

 Colloid

108

1 (0.9)

1 (2.0)

0 (0)

0 (0)

1.000

Volume of normal saline infused on D1 (ml)

112

3500 [1250–5000]

3750 [2000–6000]

2000 [1000–3500]

4000 [1500–5000]

0.013

IV insulin treatment

 Bolus

111

30 (27.0)

13 (24.5)

9 (36)

8 (24.2)

0.517

 Initial insulin infusion rate (IU/h)

112

7 [5–10]

6 [5–10]

9 [5–10]

7 [5–10]

0.356

Cumulative insulin dose (IU), per period

 Cumulative amount on D1#1

107

30 [20–50]

25 [16–42]

40 [28–60]

35 [21–50]

0.006

 Cumulative amount on D1#2

107

42 [30–60]

42 [30–60]

60 [25–65]

40 [34–60]

0.517

 Cumulative amount on D1#3

107

36 [26–60]

36 [23–50]

55 [27–73]

36 [30–60]

0.254

 Cumulative amount on D1#4

104

30 [18–51]

25 [18–40]

28 [16–75.5]

36 [18–49]

0.389

 Cumulative amount on D2#1

96

44 [28–68]

36 [25–60]

46 [27–108]

55 [36–70]

0.211

 Cumulative amount on D2#2

89

40 [30–60]

37 [24–52]

44 [33–106]

48 [32–63]

0.276

  1. Data are presented as the median [IQR] or the n (%)
  2. D1: first 24 h after filling start; U: insulin unity; D1#1: from H0 to H6; D1#2: from H6 to H12; DI#3: from H12 to H18; DI#4: from H18 to H24; D2#1: from H24 to H36; D2#2: from H36 to H48