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Table 3 Practices of high-flow nasal cannula therapy among ICU physicians (initiation, weaning, failure)

From: High-flow nasal cannula therapy: clinical practice in intensive care units

  Overall, n (%) Seniors, n (%) Juniors, n (%) p*
Minimal COT gas flow justifying a switch to HFNC     0.67
 6 L/min 40 (41/102) 38 (24/63) 44 (17/39)  
 9 L/min 39 (40/102) 43 (27/63) 33 (13/39)  
 12 L/min 12 (12/102) 10 (6/63) 15 (6/39)  
 15 L/min 9 (9/102) 10 (6/63) 8 (3/39)  
Initial HFNC settings     
 FiO2 ≥ 50% 58 (62/106) 53 (35/66) 68 (27/40) 0.16
 Gas flow ≥ 50 L/min 28 (30/106) 33 (22/66) 20 (8/40) 0.18
Criteria for HFNC failure     
 Breathing arrest 97 (103/106) 95 (40/42) 98 (63/64) 0.56
 Refractory hypoxemia 95 (104/110) 94 (63/67) 95 (41/43) 1
 Acidosis 81 (89/110) 78 (52/67) 86 (37/43) 0.33
 Worsening of ARF 95 (104/110) 100 (67/67) 86 (37/43) 0.003
 Bronchial congestion 75 (83/110) 82 (55/67) 72 (31/43) 0.24
 Circulatory insufficiency 61 (65/106) 72 (48/67) 44 (17/39) 0.007
 Agitation 95 (105/110) 99 (66/67) 91 (39/43) 0.08
 Consciousness disorders 99 (109/110) 99 (66/67) 100 (43/43) 1
 Other organ dysfunction 65 (71/109) 76 (50/66) 49 (21/43) 0.007
Criteria for HFNC weaning     0.33
 FiO2 < 30% 50 (56/111) 57 (39/68) 40 (17/43)  
 Gas flow < 20 L/min 16 (18/111) 9 (6/68) 12 (5/43)  
 Both previous criteria 30 (33/111) 25 (17/68) 37 (16/43)  
 Other 16 (18/111) 9 (6/68) 12 (5/43)  
  1. ARF: Acute respiratory failure; COT: conventional oxygen therapy; HFNC: high-flow nasal cannula
  2. *Comparisons were performed between junior and senior ICU physicians