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Annals of Intensive Care
Fig. 1 | Annals of Intensive Care

Fig. 1

From: Use of MIRUS™ for MAC-driven application of isoflurane, sevoflurane, and desflurane in postoperative ICU patients: a randomized controlled trial

Fig. 1

Study design. After intravenous induction of anesthesia in the operating room, patients obtained a balanced anesthesia with sufentanil and sevoflurane at 1.0 MAC via a standard anesthetic machine during surgery. At the end of surgery, sedation was switched to an intravenous regime with propofol for the transport from the operating room to the intensive care unit (ICU). After a minimum of 1-h intravenous sedation in the ICU, patients obtained isoflurane, sevoflurane, or desflurane at 0.5 MAC via MIRUS™. As soon as the criteria for a wake-up test were met, a spontaneous breathing trail was performed. Once patients passed the test the MAC was set to 0. The dark blue lines mark the course of the MAC throughout the study

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