Fig. 2

Comparison of microcirculatory and NIRS-derived parameters. Data are expressed as mean and standard deviation of median [interquartile range]; lines indicate individual changes. *p < 0.05, **p < 0.01 versus baseline, Two-way ANOVA for repeated measures with Sidack’s post hoc test or Friedman test with Bonferroni post hoc test, as appropriate. ^#p < 0.05 versus placebo, Two-way ANOVA for repeated measures with Sidack’s post hoc test or Mann–Whitney U test, as appropriate