Table 4 White blood cells, procalcitonin and cytokine levels
Baseline | 24 h | 72 h | p (Friedman test) | |
|---|---|---|---|---|
White blood cell count (n/mmc) | ||||
Pentaglobin (n = 10) | 9070 [5560–18,660] | 10,710 [6260–13,790] | 10,100 [7388–11,720] | 0.763 |
Placebo (n = 9) | 12,000 [6145–23,300] | 12,560 [8185–25,090] | 12,990 [7275–26,220] | 0.569 |
Procalcitonin (ng/mL) | ||||
Pentaglobin (n = 10) | 14.4 [3.4–48.6] | 14.6 [4.8, 28.8] | 7.1 [3.2–14.9]* | 0.026 |
Placebo (n = 9) | 20.0 [4.5–95.1] | 19.7 [4.6–79.9] | 5.2 [2.4–33]** | < 0.001 |
Interleukin-1 BETA (pg/mL) | ||||
Pentaglobin (n = 10) | 5.3 [4–12.8] | 4.5 [4–6.7] | 4 [4–5.6] | 0.057 |
Placebo (n = 9) | 4 [4–5.6] | 4 [4, 5] | 4 [4–5.8] | 0.376 |
Tumour necrosis factor alpha (pg/mL) | ||||
Pentaglobin (n = 10) | 32 [20–84] | 18 [14–38] | 16 [12–28] | 0.078 |
Placebo (n = 9) | 30 [24–77] | 39 [25–51]# | 19 [16–42] | 0.010 |
Interleukin-6 (pg/mL) | ||||
Pentaglobin (n = 10) | 350 [104–1418] | 166 [61–781] | 151 [41–296]* | 0.030 |
Placebo (n = 9) | 212 [52–971] | 98 [36–217] | 69 [21–141] | 0.154 |
Interleukin-8 (pg/mL) | ||||
Pentaglobin (n = 10) | 138 [52–1268] | 74 [29–177] | 75 [49–108] | 0.262 |
Placebo (n = 9) | 146 [66–302] | 62 [32–79] | 57 [45–115] | 0.278 |
Interleukin-10 (pg/mL) | ||||
Pentaglobin (n = 10) | 30 [10–118] | 9 [5–15]* | 8 [6–13]** | 0.003 |
Placebo (n = 9) | 20 [8–71] | 19 [6–29] | 10 [6–13] | 0.685 |