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Annals of Intensive Care
Fig. 2 | Annals of Intensive Care

Fig. 2

From: Surfactant protein D (SP-D) gene polymorphism rs721917 is an independent predictor of acute kidney injury development in sepsis patients: a prospective cohort study

Fig. 2

Plasma SP-D and urinary NGAL levels in septic patients. Plasma SP-D levels in septic patients with AKI KDIGO stage 1, 2, 3 and without AKI (a). Significantly higher plasma SP-D levels were observed in septic AKI stage 1 patients, which were consistent with the severity of kidney injury. Positive correlation between plasma SP-D levels and urinary NGAL levels were showed (b). Pearson analysis shows r = 0.85, 95% CI 0.80–0.89. The area under the ROC curve of plasma SP-D level, urinary NGAL level and SP-D-rs721917 CC genotype to identify the presence of AKI were 0.84, 0.91 and 0.58, respectively (c)

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