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Annals of Intensive Care
Fig. 1 | Annals of Intensive Care

Fig. 1

From: Clinical pharmacokinetics of 3-h extended infusion of meropenem in adult patients with severe sepsis and septic shock: implications for empirical therapy against Gram-negative bacteria

Fig. 1

The best fit curve (a) and the residual plot (b) of a representative patient showing one-compartment PK fitting of meropenem. a Open red dots represent meropenem concentrations at different sampling times. Curve fitting is a mathematical function that has the best fit to a series of data points. b Random distribution of residuals, i.e., difference between the observed concentration and that predicted by the model on the residual plot indicates that the model is appropriate for the data

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