Table 1 Baseline characteristics of the study group and comparison between ICU survivors versus non-survivors
From: Ocular microvascular changes in patients with sepsis: a prospective observational study
All patients (n = 48) | ICU Survivors (n = 19) | ICU Non-survivors (n = 29) | |
|---|---|---|---|
Age, years | 67 [54–77] | 58 [47–67] | 75 [61–79]* |
Male gender, n (%) | 30 (63) | 13 (68) | 17 (59) |
APACHE II score | 16 [12–21] | 13 [9–16] | 18 [14–26]* |
SOFA score at baseline | 10 [7–12] | 10 [6–11] | 12 [9–13]* |
Time after ICUadmission, h | 12 [7–17] | 12 [10–17] | 13 [4–18] |
Source of infection, n (%) | |||
Lung | 22 (46) | 11 (58) | 11 (38) |
Abdomen | 17 (35) | 5 (26) | 12 (41) |
Urinary tract | 6 (13) | 2 (11) | 4 (14) |
Soft tissue | 2 (4) | 2 (7) | |
Miscellaneous | 1 (2) | 1 (5) | |
Heart rate, bpm | 110 [86–131] | 89 [77–116] | 110 [86–131] |
Mean arterial pressure, mmHg | 73 [62–82] | 77 [69–81] | 73 [62–82] |
Cardiac index, L/min/m2 | 3.0 [2.1–3.9] | 2.9 [2.5–3.7] | 3.0 [1.7–4.2] |
Vasoactive drugs | |||
Norepinephrine, n, mcg/kg/min | 44, 0.24 [0.13–0.35] | 17, 0.24 [0.08–0.32] | 27, 0.28 [0.16–0.40] |
Epinephrine, n, mcg/kg/min | 6, 0.09 [0.06–0.23] | 6, 0.09 [0.06–0.23] | |
Dobutamine, n, mcg/kg/min | 1, 6.0 [6.0–6.0] | 1, 6.0 [6.0–6.0] | |
Hemoglobin, g/L | 105 [90–124] | 109 [98–135] | 98 [82–114]* |
White blood cells, n × 103/mmc | 13.9 [7.8–19.2] | 13.4 [7.2–17.7] | 14.0 [8.7–19.9] |
CRP, mg/L | 217 [151–282] | 252 [139–324] | 206 [161–257] |
IL-6, pg/mL | 1460 [511–4852] | 1036 [459–4487] | 1695 [511–4852] |
IL-10, pg/mL | 45 [9–135] | 26 [8–220] | 55 [11–154] |
PaO2, mmHg | 97 [80–135] | 92 [82–110] | 111 [71–148] |
Arterial lactate, mmol/L | 1.6 [1.1–3.6] | 1.1 [0.9–1.5] | 2.3 [1.5–4.9]* |