Table 1 Patients and infections characteristics on admission and on D1
From: Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database
Patients characteristics on admission | Values (n = 93) |
|---|---|
Age (years) | 62 [24–90] |
Female | 37 (40) |
BMI (kg/m2) | 25 [15–45] |
Chronic renal failure | 17 (18.2) |
SAPS 2 admission | 54 [15–124] |
Types of admission | |
Medical | 52 (56) |
Scheduled surgery | 13 (14) |
Urgent surgery | 28 (30) |
Reasons for admission | |
Septic shock | 36 (39) |
Acute respiratory failure | 30 (30.6) |
Heart failure | 8 (8.1) |
Pulmonary transplantation | 8 (8.1) |
Other | 16 (16.2) |
Clinical characteristics on D1 | Values (n = 98) |
|---|---|
Delay admission–D1 (day) | 4.5 [1–71] |
Weight (kg) | 77 [45–130] |
Temperature (°C) | 37.8 [35–41] |
Leukocytes (G/L) | 14.3 [0.1–78.7] |
Creatinine (µmol/L) | 77 [23–609] |
SOFA score | 7 [0–17] |
Vasopressors | 58 (59.1) |
Mechanical ventilation | 62 (63.3) |
Infections characteristics | |
Types of infection | |
Pulmonary | 52 (53) |
Intra-abdominal | 24 (24.5) |
Urinary | 15 (15.3) |
Cutaneous | 3 (3.1) |
Other | 4 (4) |
Bacteriemia | 14 (14.3) |
Polymicrobial infections | 46 (46.7) |
Gram-negative bacilli documented (n = 132) | |
E. coli | 41 (31.1) |
P. aeruginosa | 39 (29.5) |
E. cloacae | 10 (7.6) |
K. pneumoniae | 11 (8.3) |
Morganella spp | 8 (6.1) |
P. mirabilis | 5 (3.8) |
C. koseri | 5 (3.8) |
Others | 13 (9.8) |
Bacteria other than GNB identified | 35 (35.7) |