Table 1 Baseline characteristics of the included patients
All patients (n = 5719) | LTVV* (n = 3340) | No LTVV* (n = 2379) | p value | |
|---|---|---|---|---|
Age, years | 63.0 ± 19.2 | 60.9 ± 19.5 | 66.0 ± 18.4 | < 0.001 |
Female gender | 2441 (42.7) | 1022 (30.6) | 1419 (59.6) | < 0.001 |
Predicted body weight, kg | 60.5 ± 10.1 | 63.9 ± 9.2 | 55.7 ± 9.2 | < 0.001 |
Height, cm | 166 ± 9 | 169 ± 9 | 162 ± 9 | < 0.001 |
SAPS III | 62.3 ± 17.1 | 61.7 ± 17.4 | 63.2 ± 16.7 | 0.002 |
SOFA | 6.6 ± 3.7 | 6.5 ± 3.7 | 6.7 ± 3.7 | 0.068 |
Study phase | < 0.001 | |||
Observational | 2936 (51.3) | 1635 (49.0) | 1301 (54.7) | |
Interventional | 2783 (48.7) | 1705 (51.0) | 1078 (45.3) | |
Type of admission | < 0.001 | |||
Medical | 4326 (75.6) | 2486 (74.4) | 1840 (77.3) | |
Elective surgery | 371 (6.5) | 202 (6.0) | 169 (7.1) | |
Urgent surgery | 1022 (17.9) | 652 (19.5) | 370 (15.6) | |
Reason for ICU admission | 0.078 | |||
Postoperative care | 694 (12.1) | 419 (12.5) | 275 (11.6) | |
Acute respiratory failure | 1323 (23.1) | 752 (22.5) | 571 (24.0) | |
Cardiac arrest | 174 (3.0) | 100 (3.0) | 74 (3.1) | |
Neurological disorders | 816 (14.3) | 472 (14.1) | 344 (14.5) | |
Liver disorders | 74 (1.3) | 44 (1.3) | 30 (1.3) | |
Gastrointestinal disorders | 105 (1.8) | 59 (1.8) | 46 (1.9) | |
Sepsis | 1063 (18.6) | 601 (18.0) | 462 (19.4) | |
Shock (not considering sepsis) | 98 (1.7) | 64 (1.9) | 34 (1.4) | |
Cardiovascular disorders | 237 (4.1) | 135 (4.0) | 102 (4.3) | |
Kidney disorders | 188 (3.3) | 106 (3.2) | 82 (3.4) | |
Hematological disorders | 45 (0.8) | 20 (0.6) | 25 (1.1) | |
Others | 902 (15.8) | 568 (17.0) | 334 (14.0) | |
Co-morbidities | ||||
Cancer | 444 (7.8) | 233 (7.0) | 211 (8.9) | 0.010 |
Heart failure | 342 (6.0) | 194 (5.8) | 148 (6.2) | 0.554 |
Cirrhosis | 153 (2.7) | 98 (2.9) | 55 (2.3) | 0.176 |
AIDS | 265 (4.6) | 177 (5.3) | 88 (3.7) | 0.006 |