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Table 1 Baseline characteristics of the included patients

From: Organizational factors associated with adherence to low tidal volume ventilation: a secondary analysis of the CHECKLIST-ICU database

 All patients (n = 5719)LTVV* (n = 3340)No LTVV* (n = 2379)p value
Age, years63.0 ± 19.260.9 ± 19.566.0 ± 18.4< 0.001
Female gender2441 (42.7)1022 (30.6)1419 (59.6)< 0.001
Predicted body weight, kg60.5 ± 10.163.9 ± 9.255.7 ± 9.2< 0.001
Height, cm166 ± 9169 ± 9162 ± 9< 0.001
SAPS III62.3 ± 17.161.7 ± 17.463.2 ± 16.70.002
SOFA6.6 ± 3.76.5 ± 3.76.7 ± 3.70.068
Study phase< 0.001
 Observational2936 (51.3)1635 (49.0)1301 (54.7) 
 Interventional2783 (48.7)1705 (51.0)1078 (45.3) 
Type of admission< 0.001
 Medical4326 (75.6)2486 (74.4)1840 (77.3) 
 Elective surgery371 (6.5)202 (6.0)169 (7.1) 
 Urgent surgery1022 (17.9)652 (19.5)370 (15.6) 
Reason for ICU admission0.078
 Postoperative care694 (12.1)419 (12.5)275 (11.6) 
 Acute respiratory failure1323 (23.1)752 (22.5)571 (24.0) 
 Cardiac arrest174 (3.0)100 (3.0)74 (3.1) 
 Neurological disorders816 (14.3)472 (14.1)344 (14.5) 
 Liver disorders74 (1.3)44 (1.3)30 (1.3) 
 Gastrointestinal disorders105 (1.8)59 (1.8)46 (1.9) 
 Sepsis1063 (18.6)601 (18.0)462 (19.4) 
 Shock (not considering sepsis)98 (1.7)64 (1.9)34 (1.4) 
 Cardiovascular disorders237 (4.1)135 (4.0)102 (4.3) 
 Kidney disorders188 (3.3)106 (3.2)82 (3.4) 
 Hematological disorders45 (0.8)20 (0.6)25 (1.1) 
 Others902 (15.8)568 (17.0)334 (14.0) 
Co-morbidities
 Cancer444 (7.8)233 (7.0)211 (8.9)0.010
 Heart failure342 (6.0)194 (5.8)148 (6.2)0.554
 Cirrhosis153 (2.7)98 (2.9)55 (2.3)0.176
 AIDS265 (4.6)177 (5.3)88 (3.7)0.006
  1. Data are mean ± standard deviation or N (%)
  2. SAPS Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment, ICU intensive care unit; AIDS acquired immune deficiency syndrome
  3. * LTVV defined in tidal volume ≤ 8 ml/kg PBW in the second day of ventilation