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Table 1 Respiratory and hemodynamic parameters observed early in the course of protective mechanical ventilation in 22 COVID-19 ARDS patients

From: Respiratory mechanics and gas exchanges in the early course of COVID-19 ARDS: a hypothesis-generating study

Ventilator settings
 VT set at 6 mL/kg PBW (mL) 412 [356–425]
 RR (/min) 33 [28.5–35]
 PEEP (cmH2O) 16 [15–17]
 FiO2 (%) 45 [40–58]
Respiratory mechanics
 Pplateau (cmH2O) 27 [25–28]
 PEEPtot (cmH2O) 16.5 [16–18]
 DP (cmH2O) 9.5 [9–11.75]
 Crs (mL/cmH2O) 39.5 [33.1–44.7]
 EELV (mL) 2100 [1721–2434]
Gas exchanges
 PaCO2 (mmHg) 55 [44–62]
 PaO2/FiO2 198 [167–298]
 DAaO2 (mmHg) 136 [102–209]
 ETCO2 (mmHg) 38 [33–45]
 VR 2.9 [2.2–3.4]
 VD/VT (%) 75 [69–80.5]
 VO2 (mL/min) 280 [226–327]
 VCO2 (mL/min) 210 [175–222]
Hemodynamic support
 Catecholamine support n (%) 8 (36%)
  1. VT tidal volume, PBW predicted body weight, RR respiratory rate, Pplateau plateau pressure, PEEPtot total PEEP measured during a prolonged expiratory pause, DP driving pressure, Crs respiratory system compliance, EELV end-expiratory lung volume, DAaO2 alveolo-arterial difference in O2 partial pressures, ETCO2 end-tidal expired CO2, VR ventilatory ratio, VD/VT physiological dead space, VO2 O2 total body uptake, VCO2 CO2 total body production