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Table 5 Comparisons of clinical outcomes according to the value of CPIS and appropriateness of antimicrobial therapy

From: Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia

  CPIS value Derivation cohort Validation cohort
Appropriate antimicrobial therapy (n = 431) Inappropriate antimicrobial therapy (n = 258) P value Appropriate antimicrobial therapy (n = 95) Inappropriate antimicrobial therapy (n = 111) P value
Days on mechanical ventilation < 7 14 (8–26) 13 (8–24) 0.59 17.5 (11–32.5) 19 (12–28) 0.82
≥ 7 14 (8–26) 18 (12–29.5) 0.03 16 (11–33) 17 (11–26.5) 0.72
Days in the ICU < 7 21 (13–31) 21.5 (14–36) 0.37 24 (14.5–36) 25 (14–36.5) 0.76
≥ 7 19 (13–32) 25 (15–40.5) 0.052 20 (13–30) 20 (15–41) 0.77
ICU mortality < 7 88 (33%) 65 (34%) 0.93 19 (30%) 23 (32%) 0.82
≥ 7 62 (38%) 24 (28%) 0.12 7 (23%) 15 (39%) 0.13
  1. Data are presented as number (%) or median (interquartile range)
  2. ICU Intensive care unit; CPIS Clinical pulmonary infection score
  3. p values < 0.05 are indicated in italic characters