Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia

Annals of Intensive Care

Table 5 Comparisons of clinical outcomes according to the value of CPIS and appropriateness of antimicrobial therapy

	CPIS value	Derivation cohort			Validation cohort
	CPIS value	Appropriate antimicrobial therapy (n = 431)	Inappropriate antimicrobial therapy (n = 258)	P value	Appropriate antimicrobial therapy (n = 95)	Inappropriate antimicrobial therapy (n = 111)	P value
Days on mechanical ventilation	< 7	14 (8–26)	13 (8–24)	0.59	17.5 (11–32.5)	19 (12–28)	0.82
Days on mechanical ventilation	≥ 7	14 (8–26)	18 (12–29.5)	0.03	16 (11–33)	17 (11–26.5)	0.72
Days in the ICU	< 7	21 (13–31)	21.5 (14–36)	0.37	24 (14.5–36)	25 (14–36.5)	0.76
Days in the ICU	≥ 7	19 (13–32)	25 (15–40.5)	0.052	20 (13–30)	20 (15–41)	0.77
ICU mortality	< 7	88 (33%)	65 (34%)	0.93	19 (30%)	23 (32%)	0.82
ICU mortality	≥ 7	62 (38%)	24 (28%)	0.12	7 (23%)	15 (39%)	0.13