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Table 1 Baseline characteristics

From: Early mechanical ventilation in patients with Guillain-Barré syndrome at high risk of respiratory failure: a randomized trial

  Control group
N = 25
Experimental group
N = 25
All patients
N = 50
 
Age (years) 57 [46–70] 56 [39–67] 57 [44–69] 0.47
Male 13 (52) 15 (60) 28 (56) 0.58
Knaus score 0.21
 A 20 (80) 16 (64) 36 (72)  
 B 4 (16) 7 (28) 11 (22)  
 C 1 (4) 1 (4) 2 (4)  
 D 0 (0) 1 (4) 1 (2)  
SAPSII 21 [17–33] 30 [17–34] 26 [17–34] 0.58
MRC sumscore (/50) 38 [30–42.75] 28 [22.5–37] 33 [25–40] 0.043
Facial palsy 5 (22) 9 (39) 14 (30) 0.21
Swallowing impairment 13 (52) 12 (48) 25 (50) 1.00
FVC (ml) 1460 [1105–2335] 1726 [1206–1888] 1600 [1184–2075] 0.84
FVC (%pred) 51 [41.25–58] 47 [40–54] 49 [40–56] 0.22
MIP (cmH20) 30 [20–43] 45 [26–50] 40 [21–50] 0.21
MEP (cmH20) 32.5 [28–43·25] 50 [35–57.5] 40 [30–52.5] 0.12
FiO2 (%) 21 [21–60] 30 [21–40] 25·5 [21–43] 0.61
PaCO2 (kPa) 4.98 [4.53–5.52] 5.31 [4.56–5.6] 5.06 [4.54–5.6] 0.66
PaO2 (kPa) 10.95 [9.43–12.45] 11.8 [9.63–12.3] 11.55 [9.50–12.35] 0.54
SatO2 (%) 96.6 [95.0–98.6] 97 [93.3–98.5] 97 [94.6–98.2] 0.84
pH 7.43 [7.39–7.46] 7.43 [7.4–7.45] 7.43 [7.4–7.46] 0.74
HCO3-(mmol/L) 25·1 [22.92–26.92] 25 [23.35–27.4] 25.1 [23–27] 0.75
No immunotherapy 5 (20) 2 (8) 7 (14) 0.38
IvIg 11 (44) 17 (68) 28 (56)  
Plasma exchange 6 (24) 4 (16) 10 (20)  
IvIg and plasma exchange 3 (12) 2 (8) 5 (10)  
  1. Data are expressed as median and interquartile range for continuous variables, and as number and percentage for categorical variables
  2. SAPSII simplified acute physiology score II, MRC sumscore Medical Research Council sumscore, FVC forced vital capacity, MIP maximal inspiratory pressure, MEP maximal expiratory pressure, PaCO2 arterial pressure of carbon dioxide, PaO2 arterial pressure of oxygen, SatO2 transcutaneous saturation of oxygen, IvIg Intravenous Immunoglobulin