Skip to main content

Table 5 Risk factors for composite outcome (n = 67) versus survival without liver transplantation (n = 63) on day-60

From: pCLIF-SOFA is a reliable outcome prognostication score of critically ill children with cirrhosis: an ESPNIC multicentre study

Characteristics

Univariate analysis

Multivariable analysis

Odds ratio

p value

Odds ratio

p value

Comorbidity

0.31 (0.15–0.64)

0.002

0.16 (0.05–0.52)

0.003

Growth failure

1.88 (0.84–4.16)

0.12

  

ACLF

5.8 (1.86–18.32)

0.002

2.83 (0.77–11;11)

0.135

Sepsis

2.7(1.3–5.62)

0.005

2.1 (0.78–5.58)

0.137

Biliary atresia

1.5 (0.76–3.06)

0.23

  

INR ≥ 2.5

3.11 (1.4–6.78)

0.004

  

Bilirubin ≥ 300 μmol/L

3.5 (1.54–8.05)

0.003

  

pCLIF-SOFA

1.3 (1.18–1.5)

0.000

1.48 (1.25–1.76)

0.019

PELD

1.07 (1.03–1.13)

0.000

  
  1. Odds ratio are expressed as 95% (Confidence Interval). On multivariable analysis, centre effect was not significant (p = 0.44)
  2. ACLF acute-on-chronic liver failure, INR International Normalized Ratio, pCLIF-SOFA Paediatric Chronic Liver Failure-Sequential Organ Failure Assessment score, PELD paediatric end-stage liver disease