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Table 1 Hemodialysis model in rats: characteristics

From: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress

RRT type

Arterio-venous hemodialysis

Anesthesia

Isoflurane gas

Vascular access

Carotid artery, femoral vein

Anticoagulation

Heparinized saline 100 UI/ml: 1 ml at the beginning

Extracorporeal circuit volume

Approx. 0.7 ml (without dialyzer), 1.3 ml (with dialyzer)

Priming

NaCl 0.9% (no transfusion)

Hemodialyzer (membrane)

MicroKros® (Spectrum Lab), surface 20 cm2, 50 kDa pores, 20 cm length, fiber inner diameter 0.5 mm

Blood flow

1 ml/min, controlled with a peristaltic pump

Duration

120 min