Fig. 3
From: Ventilatory support and mechanical properties of the fibrotic lung acting as a “squishy ball”
CT scan images and transpulmonary pressure monitoring of a representative patient with UIP pattern and superimposed ground-glass during an AE-ILD, with PEEP set according to a “lung resting strategy” (left, PEEP 4 cmH2O) or with an “open lung approach” titrated to achieve positive end-expiratory transpulmonary pressure (right, PEEP 12 cmH2O). End-inspiratory transpulmonary pressure values significantly rise when higher values of PEEP are applied. Purple areas represent lung collapse, opacities and fibrous regions. Red circles highlight areas of over-inflation. AE acute exacerbation, ILD interstitial lung disease, UIP usual interstitial pneumonia, PEEP positive end-expiratory pressure