Table 3 Cox proportional hazard regression analysis for 30-day mortality
Characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Age, per 1 year increment | 1.003 (0.991–1.014) | 0.63 | 1.006 (0.993–1.019) | 0.38 |
Sex | ||||
Female | 1 [Reference] | 1 [Reference] | ||
Male | 1.113 (0.743–1.667) | 0.60 | 1.251 (0.798–1.959) | 0.33 |
HbA1c, per 1 increment | 1.045 (0.935–1.167) | 0.44 | 0.926 (0.804–1.066) | 0.28 |
Cerebrovascular disease | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 0.602 (0.317–1.146) | 0.12 | 0.432 (0.218–0.856) | 0.01 |
Chronic pulmonary disease | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 0.506 (0.328–0.779) | < 0.01 | 0.506 (0.320–0.800) | < 0.01 |
APACHE II, per 1 increment | 1.056 (1.027–1.086) | < 0.01 | 1.040 (1.008–1.073) | < 0.01 |
Lactate 0-h, per 1 mg/dL increment | 1.010 (1.005–1.014) | < 0.01 | 1.009 (1.003–1.015) | < 0.01 |
Hemoglobin, per 1 g/dL increment | 0.967 (0.818–2.672) | 0.40 | 0.983 (0.906–1.066) | 0.68 |
Creatinine, per 1 mg/dL increment | 1.048 (0.993–1.105) | 0.09 | 1.028 (0.949–1.113) | 0.50 |
Hypoglycemia episode (< 40 mg/dL) | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 2.098 (0.293–15.009) | 0.46 | 1.660 (0.209–13.203) | 0.63 |
Mean day 1 glucose, per 1 mg/dL increment | 1.004 (1.000–1.008) | 0.04 | 1.014 (1.005–1.024) | < 0.01 |
Peak day 1 glucose, per 1 mg/dL increment | 1.002 (1.000–1.004) | 0.08 | 0.993 (0.987–0.998) | 0.01 |
CoV, cut-off point 30% | ||||
Low | 1 [Reference] | 1 [Reference] | ||
High | 1.683 (1.191–2.378) | < 0.01 | 2.593 (1.494–4.499) | < 0.01 |