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Annals of Intensive Care

Table 1 Subgroup analysis of mortality in the included randomized controlled trials

From: Comparison between watchful waiting strategy and early initiation of renal replacement therapy in the critically ill acute kidney injury population: an updated systematic review and meta-analysis

Outcome/subgroup

No. of studies

No. of events/no. of patients, early group

No. of events/no. of patients, late group

Pooled odds ratio (95% CI)

I2 (%)

P for subgroup difference

Population

     

0.360

 Medical

1

138/246

128/242

1.14 (0.80 to 1.63)

0

 

 Surgical

2

46/126

77/133

0.15 (0.01 to 2.62)

85.9

 

 Mixed

6

245/609

238/582

1.02 (0.80 to 1.30)

0

 

NGAL-based

     

0.969

 No

5

321/743

315/706

0.85 (0.49 to 1.47)

75.1

 

 Yes

4

108/238

128/251

0.84 (0.54 to 1.30)

26.5

 

Emergent need for RRT

     

0.201

 Included

3

22/104

30/70

0.32 (0.06 to 1.77)

78.1

 

 Excluded

6

407/877

413/887

1.00 (0.75 to 1.32)

43

 
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