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Table 1 Patient characteristics

From: Transpulmonary thermodilution detects rapid and reversible increases in lung water induced by positive end-expiratory pressure in acute respiratory distress syndrome

Patient characteristics (n = 60)

Age (years)

69 ± 10

Male gender (n, %)

34 (57%)

Body mass index (kg/m2)

25 ± 4

Simplified Acute Physiologic Score II on inclusion

51 ± 18

ARDS severity (n, %)

 Mild

21 (35%)

 Moderate

31 (52%)

 Severe

8 (13%)

Aetiology of ARDS (n, %)

 Community acquired pneumonia

46 (77%)

 Aspiration pneumonia with neurologic disorders

5 (8%)

 Ventilator associated pneumonia

9 (15%)

ICU length of stay (days)

12 [11–38]

Total duration of mechanical ventilation (days)

11 [10–37]

Mortality at day-28 (n, %)

26 (43%)

Norepinephrine

 Number of patients (%)

54 (90%)

 Dose of norepinephrine (µg/kg/min)

0.53 [0.27–1.00]

Left ventricular ejection fraction (%)

44 ± 11

 E/e′ ratio

9 ± 2

Ventilator settings

 Tidal volume (mL/kg of PBW)

5.5 [5.0–6.0]

 Respiratory rate (breaths/min)

27 ± 5

 Fraction of inspired oxygen

0.64 ± 0.20

Patients requiring prone position (n, %)

39 (65%)

  1. ARDS: acute respiratory distress syndrome; E/e′: ratio of the amplitude of the E wave over the amplitude of the e′ wave of the mitral flow with echocardiography; ICU: intensive care unit; PBW: predicted body weight