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Table 4 Mortality rates of patients with eGFR < 30 or dialysis who received levosimendan versus dobutamine alone

From: Levosimendan use in patients with acute heart failure and reduced ejection fraction with or without severe renal dysfunction in critical cardiac care units: a multi-institution database study

Outcomes

Event (%)

Levosimendan vs. dobutamine

Levosimendan

Dobutamine

HR (95% CI)

P value

Before PSM patient numbers

52

374

  

 In-hospital mortality

14 (26.9)

114 (30.5)

0.76 (0.44–1.32)

0.330

 5-day mortality

5 (9.6)

45 (12.0)

0.79 (0.31–1.98)

0.611

 14-day mortality

11 (21.2)

76 (20.3)

1.01 (0.54–1.91)

0.968

 30-day mortality

11 (21.2)

104 (27.8)

0.73 (0.39–1.37)

0.330

 90-day mortality

14 (26.9)

132 (35.3)

0.72 (0.42–1.25)

0.247

 180-day mortality

18 (34.6)

148 (39.6)

0.83 (0.51–1.36)

0.457

After PSM patient numbers

43

81

  

 In-hospital mortality

13 (30.2)

30 (37.0)

0.67 (0.36–1.26)

0.212

 5-day mortality

4 (9.3)

10 (12.3)

0.76 (0.26–2.22)

0.611

 14-day mortality

10 (23.3)

21 (25.9)

0.87 (0.42–1.80)

0.707

 30-day mortality

10 (23.3)

28 (34.6)

0.65 (0.30–1.37)

0.254

 90-day mortality

13 (30.2)

34 (42.0)

0.68 (0.35–1.31)

0.248

 180-day mortality

17 (39.5)

36 (44.4)

0.84 (0.45–1.55)

0.573

  1. HR hazard ratio, CI confidence interval, PSM propensity score matching