From: The use of extracorporeal CO2 removal in acute respiratory failure
Partial extracorporeal support (ECCO2R) | Total extracorporeal support (ECMO) | |||||
---|---|---|---|---|---|---|
Very low flow | Low flow | Intermediate flow | Intermediate flow | High flow | High flow | |
Blood flow (L/min) | 200–400 | 400–500 | 500–1000 | 500–4500 | 2500–5000 | 2500–7000 |
Vascular access | Venovenous | Venovenous | Venovenous | Arteriovenous | Venovenous | Venovenous |
Cannula size | 13 Fr | 15.5 Fr | 18–19 Fr | 15 Fr | 27–31 Fr | Drainage: 25–29 Fr |
Cannula configuration | Dialysis catheter | Double-lumen cannula | Double-lumen cannula | Arterial and venous cannulae | Double-lumen cannula | Reinjection: 17–21 Fr |
Priming volume (mL) | 140–160 | 200–300 | 250–350 | 175 | 300–500 | 300–500 |
Anti-Xa activity (UI/L) | 0.3–0.4 | 0.3–0.4 | 0.3–0.4 | 0.3–0.4 | 0.2–0.3 | 0.2–0.3 |
Membrane surface (m2) | 0.32 | 0.59 | 0.65 | 1.3 | 1.8 | 1.8 |
CO2 extraction (% of initial value) | < 25 | 25 | 50 | 50–60 | > 50 | > 50 |
O2 transfer (mL/min) | Ø | 10 | 20 | 20–50 | 150–300 | 150–350 |