Table 1 Characteristics of patients at ICU admission*
Overall (n = 138) | Standard oxygen therapy (n = 62) | HFNO (n = 76) | p | |
|---|---|---|---|---|
Demographic and clinical characteristics | ||||
Male—no. (%) | 112 (81%) | 50 (81%) | 62 (82%) | 1.00 |
Median age, years (IQR) | 59 (48–67) | 60 (51–67) | 60 (52–67) | 0.64 |
Immunocompromized patient—no. (%) | 20 (14%) | 9 (14%) | 11 (14%) | 1.00 |
Diabetes—no. (%) | 43 (31%) | 19 (31%) | 24 (32%) | 1.00 |
Hypertension—no. (%) | 56 (41%) | 19 (31%) | 37 (49%) | 0.049 |
Chronic respiratory failure—no. (%) | 4 (3%) | 2 (3%) | 2 (3%) | 1.00 |
Chronic kidney failure—no. (%) | 7 (5%) | 3 (5%) | 4 (5%) | 1.00 |
Median BMI, kg/m2 (IQR) | 29 (26–33) | 27 (26–33) | 29 (25–33) | 0.59 |
Median SAPS II (IQR) | 36 (26–46) | 35 (26–45) | 36 (27–47) | 0.62 |
Median time from onset symptoms to ICU admission, days (IQR) | 10 (8–13) | 8 (8–13) | 10 (8–13) | 0.002 |
Respiratory finding | ||||
Median 02 flow, liter/minute (IQR) | 9 (4–12) | 6 (5–13) | 9 (6–15) | 0.003 |
Median PaO2, mmHg (IQR) | 71 (64–84) | 71 (63–85) | 69 (63–82) | 0.45 |
Median respiratory rate, (IQR) | 30 (27–35) | 30 (26–35) | 33 (28–36) | 0.018 |
Median O2 maximal flow rate, Liter/minute, (IQR) | 12 (9–15) | 12 (9–15) | 12 (9–15) | 0.049 |
Laboratory finding | ||||
Median Lymphocyte, G/L (IQR) | 0.8 (0.6–1.1) | 0.9 (0.6–1.1) | 0.8 (0.6–1.0) | 0.10 |
Median Fibrinogen, g/L (IQR) | 6.59 (5.9–7.3) | 6.57 (6.0–7.3) | 6.7 (6.2–7.3) | 0.50 |
Median Phosphor, mmol/L (IQR) | 0.82 (0.69–0.95) | 0.8 (0.71–0.94) | 0.84 (0.70–0.94) | 0.29 |
Median CRP, mmol/L (IQR) | 182 (114–263) | 182 (106–262) | 182 (125–269) | 0.64 |
Median ferritin, µg/L (IQR) | 1502 (874–2530) | 1137 (880–2495) | 1701 (885–2677) | 0.036 |
Chest CT scan finding | ||||
Median ground glass surface, % (IQR) | 50 (25–60) | 50 (25–60) | 50 (25–60) | 0.27 |
Steroids during ICU stay—no.(%) | 66 (48%) | 25 (40%) | 41 (54%) | 0.15 |