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Annals of Intensive Care

Table 2 Patient characteristics during PICU stay according to outcome

From: Malignant pertussis in infants: factors associated with mortality in a multicenter cohort study

 

Non-survivors

(n = 9)

Survivors

(n = 14)

p

All patients

(n = 23)

Cardiovascular failure, n (%)

9 (100)

5 (36)

0.003

14 (61)

Pulmonary hypertension, n (%)

9 (100)

4 (29)

0.002

13 (56)

Kidney failure, n (%)

8 (89)

3 (21)

0.003

11 (48)

Anuria, n (%)

9 (100)

3 (21)

< 0.001

12 (52)

Neurological failure, n (%)

3 (33)

6 (43)

1

9 (39)

Liver failure, n (%)

5 (56)

2 (14)

0.049

7 (30)

Documented bacterial superinfection, n (%)a

6 (67)

8 (57)

1

14 (61)

Documented viral co-infection, n (%)b

4 (44)

5 (36)

1

9 (39)

Hematological failure, n (%)

5 (56)

2 (14)

0.02

7 (30)

Secondary thrombopenia, n (%)

7 (78)

6 (43)

0.19

13 (57)

Minimal sodium level, mmol/l, median [IQR]

122 [119–125]

131 [129–135]

0.003

130 [122–135]

Maximal lactate, mmol/l, median [IQR]

9 [3–16]

3 [2–4]

0.02

3 [2–9]

Minimal pH, median [IQR]

7.05 [6.8–7.1]

7.24 [7.17–7.32]

0.002

7.18 [7.05–7.26]

Maximal pCO2, kPa, median [IQR]

9.1 [8.7–12.3]

8.3 [7.0–11.0]

0.25

9.0 [7.7–11.5]

Maximal creatinine, µmol/l, median [IQR]

81 [49–110]

27 [23–51]

0.002

40 [25–82]

Maximal C-reactive protein, mg/l, median [IQR]

203 [135–237]

90 [7–205]

0.11

135 [30–217]

Maximal procalcitonin, µg/l, median [IQR]

19.0 [6.3–23.7]

1.0 [0.2–4.3]

0.012

3.3 [0.5–19.3]

WBC growth, G/l/day, median [IQR]

21 [10–28]

6 [3–7]

0.007

6 [3–17]

Maximal WBC count, G/l, median [IQR]

88 [63–95]

65 [53–81]

0.12

71 [56–91]

Maximal neutrophils, G/l, median [IQR]

41 [23–47]

25 [16–37]

0.14

26 [18–46]

Maximal lymphocytes, G/l, median [IQR]

33 [26–34]

33 [28–39]

0.83

32 [28–37]

Lymphocyte/neutrophil ratio < 1, n (%)

8 (89)

3 (21)

0.003

12 (52)

  1. aStenotrophomonas maltophilia (1), SAMS (4), Escherichia coli (2), Klebsiella pneumoniae + Citrobacter koseri (1), Streptococcus pneumoniae (2), Enterobacter cloacae (1), other GNB (1), Haemophilus influenzae (1), Corynebacterium (1) were identified through tracheal (1), nasopharyngeal (7), blood culture (5), and bronchoalveolar lavage (1) samples
  2. bRhinovirus (3), Picornavirus (3), Bocavirus (1), Influenza B (1), RSV (3), were identified through nasopharyngeal samples (8)
  3. IQR  interquartile range; pCO2 partial pressure of carbon dioxide; PELOD pediatric logistic organ dysfunction; PICU pediatric intensive care unit; SpO2/FiO2 ratio pulse oximetry saturation/fraction of inspiratory oxygen; WBC white blood cell
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