Table 3 Factors associated with day 28 mortality

Age per year

1.05

1.02–1.07

 < 0.001

Normal troponin at ICU admission

0.42

0.25–0.70

0.001

 COPD

2.67

1.37–5.22

0.004

 Underlying immune defect

1.97

1.22–3.18

0.005

AKI

1.35

0.78–2.32

0.28

Delay since disease onset < 8 days

Ref

–

NA

Delay since disease onset 8 to 14 days

0.51

0.35–0.80

0.004

Delay since disease onset > 14 days

0.39

0.15–0.98

0.05

 Center effect (frailty)

0.02