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Table 3 Clinical Outcomes at 28 days

From: Protective ventilation and outcomes of critically ill patients with COVID-19: a cohort study

Outcomes

All, n = 1503

Survivors, n = 837

Nonsurvivors, n = 666

p value

ICU length of stay, median (IQR), d

10 (6–18)

10 (5–21)

10 (6–16)

0.119

Hospital length of stay, median (IQR), d

16 (11–26)

21 (14–33)

13 (8–19)

 < 0.001

Invasive mechanical ventilation

1180 (79)

552 (66)

628 (94)

 < 0.001

Duration of mechanical ventilation, median (IQR), d

10 (6–17)

9 (5 – 18)

11 (6–16)

0.303

Prone positioning

427 (36)

201 (36)

226 (36)

0.570

Use of noninvasive ventilationa

320 (21)

165 (20)

155 (23)

0.012

Use of high-flow nasal cannulaa

139 (9)

84 (10)

55 (8)

0.031

Extracorporeal membrane oxygenation

10 (1)

3 (1)

7 (1)

0.186

Vasopressors

1095 (73)

478 (57)

617(93)

 < 0.001

Renal replacement therapy

528 (35)

187 (22)

341 (51)

 < 0.001

Tracheostomy

169 (11))

116 (14)

53 (8)

 < 0.001

Delirium

223 (15)

119 (14)

104 (16)

0.494

Ventilator-associated pneumonia

393(26)

175 (21)

218 (33)

 < 0.001

Thromboembolic event

279 (19)

143 (17)

136 (20)

0.11

Cardiac arrhythmia

263 (17%)

101 (12)

162 (24)

 < 0.001

Treatment withhold or withdraw during ICU stay

288 (19)

55 (7)

233 (35)

 < 0.001

  1. ICU: intensive care unit; IQR: interquartile range; Data are n. (%), unless otherwise stated
  2. aTo avoid intubation or prior to intubation. Comparisons were made with t test, Mann–Whitney U tests or chi-square test as appropriate