From: Protective ventilation and outcomes of critically ill patients with COVID-19: a cohort study
Outcomes | All, n = 1503 | Survivors, n = 837 | Nonsurvivors, n = 666 | p value |
---|---|---|---|---|
ICU length of stay, median (IQR), d | 10 (6–18) | 10 (5–21) | 10 (6–16) | 0.119 |
Hospital length of stay, median (IQR), d | 16 (11–26) | 21 (14–33) | 13 (8–19) |  < 0.001 |
Invasive mechanical ventilation | 1180 (79) | 552 (66) | 628 (94) |  < 0.001 |
Duration of mechanical ventilation, median (IQR), d | 10 (6–17) | 9 (5 – 18) | 11 (6–16) | 0.303 |
Prone positioning | 427 (36) | 201 (36) | 226 (36) | 0.570 |
Use of noninvasive ventilationa | 320 (21) | 165 (20) | 155 (23) | 0.012 |
Use of high-flow nasal cannulaa | 139 (9) | 84 (10) | 55 (8) | 0.031 |
Extracorporeal membrane oxygenation | 10 (1) | 3 (1) | 7 (1) | 0.186 |
Vasopressors | 1095 (73) | 478 (57) | 617(93) |  < 0.001 |
Renal replacement therapy | 528 (35) | 187 (22) | 341 (51) |  < 0.001 |
Tracheostomy | 169 (11)) | 116 (14) | 53 (8) |  < 0.001 |
Delirium | 223 (15) | 119 (14) | 104 (16) | 0.494 |
Ventilator-associated pneumonia | 393(26) | 175 (21) | 218 (33) |  < 0.001 |
Thromboembolic event | 279 (19) | 143 (17) | 136 (20) | 0.11 |
Cardiac arrhythmia | 263 (17%) | 101 (12) | 162 (24) |  < 0.001 |
Treatment withhold or withdraw during ICU stay | 288 (19) | 55 (7) | 233 (35) |  < 0.001 |