Table 4 Variables associated with intra-dialytic hypotension (using Definition 2A)

Model 1: before CRRT discontinuation

 Mechanical ventilation

1.87 (0.79; 4.44) 0.155

1.35 (0.47; 3.89) 0.579

 Cumulative fluid balance (per L)

1.03 (1.01; 1.06) 0.009

1.04 (1.01; 1.06) 0.013

 24-h urine output (per 100 mL)

0.91 (0.83; 0.999) 0.047

0.90 (0.82; 0.98) 0.017

 Time on CRRT (per day)

1.04 (0.99; 1.08) 0.093

1.04 (0.99; 1.10) 0.095

 Vasopressor use

3.16 (1.80; 5.54) < 0.001

3.29 (1.84; 5.89) < 0.001

 Number of past transitions attempts

1.96 (0.99; 3.88) 0.052

1.08 (0.46–2.52) 0.856

Model 2: before IRRT initiation

 Heart rate (per 10 beats/min)

1.06 (0.92; 1.21) 0.432

1.07 (0.90; 1.27) 0.428

 sBP (per 10 mmHg)

0.75 (0.65; 0.86) < 0.001

0.85 (0.73; 0.999) 0.05

 dBP (per 10 mmHg)

0.65 (0.51; 0.82) < 0.001

0.79 (0.59; 1.05) 0.107

 Mechanical ventilation

2.93 (1.24; 6.89) 0.014

2.12 (0.85; 5.29) 0.109

 Vasopressor use

3.95 (2.26; 6.91) < 0.001

2.22 (1.11; 4.43) 0.024

 Prescribed relative fluid removal (% of BW)

1.76 (0.25; 12.35) 0.571

1.26 (1.01; 1.59) 0.043

 Time gap between CRRT and IRRT (days)

0.74 (0.57; 0.97) 0.029

0.99 (0.98; 1.00) 0.162

 Prescribed treatment time (hours)

1.51 (CI: 1.29; 1.76) < 0.001

1.33 (1.12; 1.59) 0.001