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Table 4 Variables associated with intra-dialytic hypotension (using Definition 2A)

From: Intra-dialytic hypotension following the transition from continuous to intermittent renal replacement therapy

Variable Univariable OR (95%CI) p-value Multivariable Adj OR (95%CI) p-value
Model 1: before CRRT discontinuation
 Mechanical ventilation 1.87 (0.79; 4.44) 0.155 1.35 (0.47; 3.89) 0.579
 Cumulative fluid balance (per L) 1.03 (1.01; 1.06) 0.009 1.04 (1.01; 1.06) 0.013
 24-h urine output (per 100 mL) 0.91 (0.83; 0.999) 0.047 0.90 (0.82; 0.98) 0.017
 Time on CRRT (per day) 1.04 (0.99; 1.08) 0.093 1.04 (0.99; 1.10) 0.095
 Vasopressor use 3.16 (1.80; 5.54) < 0.001 3.29 (1.84; 5.89) < 0.001
 Number of past transitions attempts 1.96 (0.99; 3.88) 0.052 1.08 (0.46–2.52) 0.856
Model 2: before IRRT initiation
 Heart rate (per 10 beats/min) 1.06 (0.92; 1.21) 0.432 1.07 (0.90; 1.27) 0.428
 sBP (per 10 mmHg) 0.75 (0.65; 0.86) < 0.001 0.85 (0.73; 0.999) 0.05
 dBP (per 10 mmHg) 0.65 (0.51; 0.82) < 0.001 0.79 (0.59; 1.05) 0.107
 Mechanical ventilation 2.93 (1.24; 6.89) 0.014 2.12 (0.85; 5.29) 0.109
 Vasopressor use 3.95 (2.26; 6.91) < 0.001 2.22 (1.11; 4.43) 0.024
 Prescribed relative fluid removal (% of BW) 1.76 (0.25; 12.35) 0.571 1.26 (1.01; 1.59) 0.043
 Time gap between CRRT and IRRT (days) 0.74 (0.57; 0.97) 0.029 0.99 (0.98; 1.00) 0.162
 Prescribed treatment time (hours) 1.51 (CI: 1.29; 1.76) < 0.001 1.33 (1.12; 1.59) 0.001
  1. Associations were assessed using generalized estimating equations with a binary logistic link function and using an M-estimator with an independent correlation matrix
  2. Adj adjusted, BW body weight, 95%CI 95% confidence interval, CRRT continuous renal replacement therapy, dBP diastolic arterial blood pressure, IRRT intermittent renal replacement therapy, OR odds ratio, sBP systolic arterial blood pressure