Study | Intervention | Population | Total patients N | Total ECMO use n (% of N) | ECMO use in intervention group n (% of N) |
---|---|---|---|---|---|
ACURASYS [95] | Cisatracurium | Severe ARDS (PF ratio < 150 mmHg) | 339 | 0 (0) | 0 (0) |
ART [120] | Lung recruitment maneuvers | Moderate-to-severe ARDS (PF ratio ≤ 200 mmHg) | 1010 | 10 (0.99) | 5 (0.5) |
EPVENT-2 [121] | Transpulmonary pressure targets | Moderate-to-severe ARDS (PF ratio ≤ 200 mmHg) | 200 | 4 (2.0) | 1 (0.5) |
ICU-ROX [122] | Conservative oxygen | PF ratio < 300 mmHg | 623 | 13a (2.09) | 7a (1.12) |
LIVE [123] | Personalized mechanical ventilation | Moderate-to-severe ARDS (PF ratio ≤ 200 mmHg) | 400 | 14 (3.5) | 7 (1.75) |
LOCO2 [124] | Liberal oxygen | Mild-to-severe ARDS (PF ratio ≤ 300 mmHg) | 201 | 0 (0) | 0 (0) |
LUNG SAFE [73] | NA | Mild-to-severe ARDS (PF ratio ≤ 300 mmHg) | 2377 | 76 (3.2) | N/A |
PHARLAP [125] | Lung recruitment maneuvers | Moderate-to-severe ARDS (PF ratio ≤ 200 mmHg) | 114 | 7 (6.14) | 1 (0.88) |
PROSEVA [68] | Prone positioning | Severe ARDS (PF < 150 mmHg) | 466 | 8 (1.72) | 2 (0.43) |
ROSE [69] | Cisatracurium | Moderate-to-severe ARDS (PF ≤ 200 mmHg) | 1006 | 13 (1.29) | 3 (0.30) |
Total | Â | Â | 6736 | 145 (2.15) | Â |