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Table 2 Patient characteristics and laboratory measurements after PS matching analysis

From: Can the cytokine adsorber CytoSorb® help to mitigate cytokine storm and reduce mortality in critically ill patients? A propensity score matching analysis

 

Group 1: n (%) or mean [range: min, max]

Group 2: n (%) or mean [range: min, max]

p-value (U-test/Fisher test)

Difference from mean (%)

Number

19 (100)

19 (100)

  

Patient characteristics

 ECMO therapy

4 (21.0)

4 (21.0)

1.00

0.0

 KRT

19 (100)

19 (100)

1.00

0.0

 SAPS II d0

77 [38, 118]

75 [48, 100]

0.644

1.7

 48-h mortality

1 (5.3)

3 (15.8)

0.583

 

 In-hospital mortality

14 (73.7)

14 (73.7)

1.00

 

 Surgical intervention

9 (47.4)

8 (42.1)

0.79

 

Laboratory measurements

 IL-6 d0 (pg/ml)

58,385 [10,108, 206,000]

59,812 [10,051, 600,000]

0.181

1.2

 IL-6 d1 (pg/ml)

16,314 [461, 123,000]

27,445 [30, 260,000]

  

 CRP d0 (mg/dl)

14.5 [0.3, 47.1]

16.3 [0.1, 46.9]

0.817

5.8

 CRP d1 (mg/dl)

13.8 [0.7, 28.1]

20.9 [1.1, 41.6]

  

 Lactate d0 (mmol/l)

7.8 [1.0, 17.6]

8.2 [0.8, 26.0]

0.729

2.5

 Lactate d1 (mmol/l)

8.6 [1.2, 17]

6.7 [0.9, 18]

  

 Nor d0 (mg/h)

3.8 [0.9, 8.0]

3.6 [0.0, 16.0]

0.223

2.7

 Nor d1 (mg/h)

2.8 [0.4, 11.5]

2.3 [0.3, 6.0]

  
  1. d0: 0–12 h before starting CS therapy (group 1) or the measured IL-6 > 10,000 pg/ml (group 2), d1: 12–24 h after starting CS therapy (group 1) or 12–24 h after d0 IL-6 (group 2)
  2. BMI body mass index, ECMO extracorporeal membrane oxygenation, ICU intensive care unit, SAPS Simplified Acute Physiology Score, CRP C-reactive protein, Nor norepinephrine