Impact of ICU transfers on the mortality rate of patients with COVID-19: insights from comprehensive national database in France

Annals of Intensive Care

Table 3 Univariate and multivariate mortality models of patients with COVID-19 still hospitalized on Day 5 in intensive care unit (ICU) from 1 March to 21 June 2020

	Risk ratio	95% CI	P-value	Risk ratio	95% CI	P-value
Age
≤ 29 years	1			1
30–39 years	2.145	1.184–3.885	0.0118	2.018	1.164–3.501	0.0124
40–49 years	1.957	1.121–3.415	0.0181	1.873	1.142–3.075	0.0130
50–59 years	3.473	2.041–5.912	< 0.0001	3.299	2.044–5.322	< 0.0001
60–69 years	5.179	3.056–8.776	< 0.0001	5.057	3.152–8.112	< 0.0001
70–79 years	6.935	4.095–11.747	< 0.0001	6.883	4.292–11.039	< 0.0001
≥ 80 years	8.314	4.885–14.150	< 0.0001	8.966	5.574–14.42	< 0.0001
Sex (male vs female)	1.147	1.060–1.240	0.0006	1.177	1.103–1.255	< 0.0001
Hospitalization time period
Up to 23 March 2020
23–29 March 2020	0.777	0.710–0.851	< 0.0001	0.842	0.780–0.910	< 0.0001
30 March to 05 April 2020	0.739	0.666–0.819	< 0.0001	0.787	0.726–0.853	< 0.0001
06–19 April 2020	0.789	0.709–0.878	< 0.0001	0.789	0.722–0.861	< 0.0001
20 April 2020 to 21 June 2020	0.578	0.504–0.663	< 0.0001	0.580	0.514–0.655	< 0.0001
Region with high incidence (vs others^a)	1.347	1.243–1.459	< 0.0001	1.547	1.441–1.659	< 0.0001
Hospital type
Public hospital vs university hospital	0.972	0.901–1.048	0.4584	0.940	0.881–1.003	0.0597
Private hospital vs university hospital	0.868	0.785–0.960	0.0059	0.774	0.710–0.844	< 0.0001
Location before ICU admission (Hospital vs Home)	0.958	0.892–1.029	0.2442	0.942	0.888–0.999	0.0468
ICU transfer
Less than 10 km	0.941	0.802–1.105	0.4588	1.005	0.870–1.159	0.9512
10–50 km	0.800	0.677–0.946	0.0089	0.819	0.702–0.956	0.0114
50–200 km	0.864	0.709–1.052	0.1454	0.788	0.642–0.967	0.0228
200 km and more	0.440	0.338–0.573	< 0.0001	0.392	0.298–0.514	< 0.0001