Table 3 Breathing pattern and blood gases at baseline (PSV-Baseline), after personalization of ventilator settings (PSV-Personalization) and with proportional assist ventilation (PAV)
PSV-Baseline | PSV-Personalization | PAV | p | |
|---|---|---|---|---|
Breathing pattern | ||||
RR, min‒1 | 27 (22‒32) | 24 (20‒30)* | 21 (17‒28)*§ | < 0.0001 |
Vt, ml/kg IBW | 7.0 (5.6‒9.7) | 7.8 (7.0‒9.8)* | 9.0 (6.5‒10.5)* | < 0.0001 |
Ti, sec | 0.75 (0.61‒0.95) | 0.85 (0.67‒1.03) | 0.97 (0.82‒1.27)*§ | < 0.0001 |
Vt/ Ti, L/s‒1 | 1.15 (0.74‒1.55) | 1.97 (1.23‒3.16)* | 0.84 (0.62‒1.06)§ | < 0.0001 |
Pmax, cmH2O | 13 (12‒15) | 21 (18‒23) * | 24 (19‒29)* | < 0.0001 |
EtCO2, mmHg | 33 (28‒38) | 31 (26‒35) | 31 (27‒37) | 0.033 |
Breath-by-breath variability | ||||
CV RR, % | 13 (10–20) | 14 (11–24) | 22 (15–28) * § | 0.001 |
CV Vt, % | 15 (11–20) | 15 (10–26) | 25 (17–43) * § | < 0.001 |
CV Ti, % | 22 (16–43) | 33 (19–50) | 22 (13–27) § | 0.023 |
CV Vt/ Ti, % | 23 (16–39) | 29 (15–42) | 23 (14–60) | 0.632 |
CV Pmax, % | 4 (4–06) | 6 (3–10) | 16 (11–23) * § | < 0.001 |
Blood gases | ||||
pH | 7.43 (7.36‒7.44) | 7.41 (7.39‒7.47)* | 7.42 (7.37‒7.48)* | 0.012 |
PaO2, mmHg | 80 (73‒99) | 87 (73‒101) | 88 (79‒98)* | 0.016 |
PaCO2, mmHg | 41 (36‒49) | 39 (34‒47)* | 39 (33‒48) | 0.001 |
SaO2, % | 96 (94‒98) | 96 (94‒98) | 97 (96‒98) | 0.038 |
HCO3−, mmol/L | 26.6 (22.7‒28.9) | 26.8 (22.7‒29.4) | 26.9 (22.1‒28.6) | 0.503 |
A-aO2 gradient, mmHg | 94 (72‒154) | 96 (85‒158) | 82 (64‒143) § | 0.023 |