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Table 1 Baseline patient characteristics

From: Prevention of ventilator-associated pneumonia by noble metal coating of endotracheal tubes: a multi-center, randomized, double-blind study

Patient characteristics NMA-coated group Control group p value
Number 168 155  
Gender female, n (%) 75 (44.6) 69 (44.5) 0.98
Age in years, median (Q1–Q3) 67.9 (56.4–74.7) 67.3 (58–74.5) 0.98
Type of patients, n (%)    0.58
 Medical 139 (82.7) 127 (82)  
 Surgical 24 (14.3) 20 (12.9)  
 Trauma 5 (3) 8 (5.2)  
Reason for admission, n (%)    0.13
 Neuro 39 (24.7) 21 (14.7)  
 Cardiac 21 (13.3) 29 (20.3)  
 Respiratory 53 (33.5) 46 (32.2)  
 Digestive 18 (11.4) 25 (17.5)  
 Kidney 2 (1.3) 5 (3.5)  
 Sepsis 15 (9.5) 10 (7)  
 Other 10 (6.3) 7 (4.9)  
Charlson score, median (Q1–Q3) 2 (1–4) 2 (1–4) 0.77
SAPS II, median (Q1–Q3) 48 (38–60) 48 (40–62) 0.85
SOFA 1st day, median (Q1–Q3) 8 (6–10) 8 (6–11) 0.06
Antibiotic therapy on intubation, n (%) 119 (70.8) 121 (78.1) 0.14
Reason, n (%)    0.048
 Central nervous system infection 3 (1.8) 3 (1.9)  
 Respiratory infection 79 (47) 60 (38.7)  
 Intra-abdominal infection 5 (3) 17 (11)  
 Urinary tract infection 6 (3.6) 7 (4.5)  
 Sepsis 14 (8.3) 13 (8.4)  
 Soft tissue infection 3 (1.8) 2 (1.3)  
 Prophylaxis 4 (2.4) 6 (3.9)  
 Other 5 (3) 13 (8.4)  
Type of antibiotic therapy given on intubation, n (%)    0.10
 None 53 (31.6) 35 (22.6)  
 Amoxycillin–clavulanic acid 25 (21) 27 (22.3)  
 Third generation cephalosporin 16 (13.5) 29 (24)  
 Large spectrum antibioticsa 62 (52.1) 54 (44.6)  
 Otherb 12 (10.1) 10 (8.3)  
  1. aCarbapenem, piperacillin–tazobactam, cefepime
  2. bFlucloxacillin, vancomycin, fluoroquinolone, trimethoprim–sulfamethoxazole, amoxycillin
  3. Q quartile; SAPS Simplified Acute Physiology Score; SOFA Sequential Organ Failure Assessment