Table 1 Baseline patient characteristics
Patient characteristics | NMA-coated group | Control group | p value |
|---|---|---|---|
Number | 168 | 155 | |
Gender female, n (%) | 75 (44.6) | 69 (44.5) | 0.98 |
Age in years, median (Q1–Q3) | 67.9 (56.4–74.7) | 67.3 (58–74.5) | 0.98 |
Type of patients, n (%) | 0.58 | ||
Medical | 139 (82.7) | 127 (82) | |
Surgical | 24 (14.3) | 20 (12.9) | |
Trauma | 5 (3) | 8 (5.2) | |
Reason for admission, n (%) | 0.13 | ||
Neuro | 39 (24.7) | 21 (14.7) | |
Cardiac | 21 (13.3) | 29 (20.3) | |
Respiratory | 53 (33.5) | 46 (32.2) | |
Digestive | 18 (11.4) | 25 (17.5) | |
Kidney | 2 (1.3) | 5 (3.5) | |
Sepsis | 15 (9.5) | 10 (7) | |
Other | 10 (6.3) | 7 (4.9) | |
Charlson score, median (Q1–Q3) | 2 (1–4) | 2 (1–4) | 0.77 |
SAPS II, median (Q1–Q3) | 48 (38–60) | 48 (40–62) | 0.85 |
SOFA 1st day, median (Q1–Q3) | 8 (6–10) | 8 (6–11) | 0.06 |
Antibiotic therapy on intubation, n (%) | 119 (70.8) | 121 (78.1) | 0.14 |
Reason, n (%) | 0.048 | ||
Central nervous system infection | 3 (1.8) | 3 (1.9) | |
Respiratory infection | 79 (47) | 60 (38.7) | |
Intra-abdominal infection | 5 (3) | 17 (11) | |
Urinary tract infection | 6 (3.6) | 7 (4.5) | |
Sepsis | 14 (8.3) | 13 (8.4) | |
Soft tissue infection | 3 (1.8) | 2 (1.3) | |
Prophylaxis | 4 (2.4) | 6 (3.9) | |
Other | 5 (3) | 13 (8.4) | |
Type of antibiotic therapy given on intubation, n (%) | 0.10 | ||
None | 53 (31.6) | 35 (22.6) | |
Amoxycillin–clavulanic acid | 25 (21) | 27 (22.3) | |
Third generation cephalosporin | 16 (13.5) | 29 (24) | |
Large spectrum antibioticsa | 62 (52.1) | 54 (44.6) | |
Otherb | 12 (10.1) | 10 (8.3) |