Table 1 Baseline characteristics of included patients (prior to first SLED session)
Characteristic | Saline (n = 30) | Albumin (n = 30) | Overall (n = 60) |
|---|---|---|---|
Age in years, mean (SD) | 60 (18) | 61 (13) | 60 (15) |
Female, n (%) | 9 (30) | 6 (20) | 15 (25) |
APACHE II total score, mean (SD) | 29.9 (8.2) | 30.3 (8.1) | 30.1 (8) |
SOFA score components prior to first SLED session, median (IQR) | |||
Respiration | 2 (1,3) | 2 (2,3) | 2 (1.75,3) |
Coagulation | 1 (0,2) | 1 (0,2) | 1 (0,2) |
Liver | 1 (0,2) | 1 (0,2) | 1 (0,2) |
Cardiovascular | 4 (3,4) | 4 (3,4) | 4 (3,4) |
Central nervous system | 1 (0,2) | 1 (0,1.75) | 1 (0,2) |
Renal | 4 (3.5,4) | 4 (4,4) | 4 (4,4) |
Total | 13 (10,15) | 12.5 (10.5,14) | 12.5 (10,15) |
Comorbid conditions, n (%) | |||
Diabetes mellitus | 13 (43) | 10 (33) | 23 (38) |
Congestive heart failure | 1 (3) | 1 (3) | 2 (3) |
Peripheral vascular disease | 3 (10) | 6 (20) | 9 (15) |
Chronic kidney disease | 6 (20) | 9 (30) | 15 (25) |
Primary ICU admission diagnosis, n (%) | |||
Septic/distributive shock | 19 (63) | 22 (73) | 41 (68) |
Respiratory failure | 4 (13) | 5 (17) | 9 (15) |
Other | 7 (23) | 3 (10) | 10 (17) |
Indications for SLED Initiation, n (%) | |||
Pulmonary edema | 16 (53) | 14 (47) | 30 (50) |
Uremia | 1 (3) | 0 (0) | 1 (2) |
Hyperkalemia | 8 (27) | 17 (57) | 25 (42) |
Acidosis | 13 (43) | 14 (47) | 27 (45) |
Other | 2 (7) | 1 (3) | 3 (5) |
Laboratory parameters prior to first SLED session, mean (SD) | |||
Albumin (g/L) | 25 (7) | 23 (8) | 24 (7) |
Creatinine (µmol/L) | 320 (168) | 357 (188) | 338 (178) |
Urea (mmol/L) | 21.6 (11.9) | 27.6 (13.5) | 24.5 (12.9) |
Potassium (mmol/L) | 4.6 (0.9) | 5.0 (0.9) | 4.8 (1.0) |
Calcium (mmol/L) | 2.02 (0.24) | 2.01 (0.26) | 2.01 (0.24) |
Ionized calcium (mmol/L) | 1.06 (0.11) | 1.03 (0.1) | 1.05 (0.11) |
Phosphate (mmol/L) | 2.02 (0.83) | 2.16 (0.93) | 2.09 (0.87) |
Lactate (mmol/L) | 3.0 (3.2) | 4.5 (5.8) | 3.7 (4.6) |
Hemoglobin (g/L) | 90 (19) | 91 (21) | 91 (20) |
White blood cells (×109/L) | 14.7 (12.6) | 14.8 (11.5) | 14.7 (12.0) |