Author reply in response to a letter on “High-flow nasal oxygen cannula vs. noninvasive mechanical ventilation to prevent reintubation in sepsis: a randomized controlled trial”

Annals of Intensive Care

Table 1 Pulmonary mechanic parameters of the patients

Pulmonary mechanic parameters, median (IQR)	NIV (N = 110)	HFNC (N = 112)	P
Peak inspiratory pressure (cmH₂O)	16 (14–18)	16 (14–20)	0.38
Plateau pressure (cmH₂O)	12 (10–14)	12 (10–15)	0.59
Positive end expiratory pressure (PEEP, cmH₂O)	5 (5–6)	5 (5–5)	0.45
Tidal volume (mL/kg)	7.1 (5.7–8.6)	7.1 (6.0–8.8)	0.99
Fraction of inspired oxygen (FiO₂, %)	40 (40–40)	40 (40–50)	0.45
Respiratory system static compliance^a (mL/cmH₂O)	80 (50–130)	70 (50–100)	0.14
Airway resistance^b (cmH₂O/L/s)	4 (4–5)	4 (4–5)	0.48

NIV noninvasive ventilation, HFNC high-flow nasal oxygen cannular, SD standard deviation, IQR interquartile range: cmH₂O centimetre of water, mL/kg millilitre per kilogramme, mL/cmH₂O millilitre per centimetre of water, cmH₂O/L/sec centimetre of water per litre per second, ABG arterial blood gas analysis, PaO₂ partial pressure of oxygen in arterial blood, PaCO₂ partial pressure of carbon dioxide in arterial blood, FiO₂ fraction of inspired oxygen, mmHg millimetre of mercury
^aNormal respiratory system static compliance is 60–100 mL/cmH₂O
^bNormal airway resistance is less than 5 cmH₂O/L/s