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Annals of Intensive Care
Fig. 3 | Annals of Intensive Care

Fig. 3

From: Effects of regional citrate anticoagulation on thrombin generation, fibrinolysis and platelet function in critically ill patients receiving continuous renal replacement therapy for acute kidney injury: a prospective study

Fig. 3

Changes in circuit measurements of coagulation over duration of treatment. INR International Normalised Ratio, APTTr activated partial thromboplastin time ratio, TGA thrombin generation assay, PFSCA platelet function assay using collagen/adenosine diphosphate, PFSCE platelet function assay using collagen/epinephrine, CT closure time. Repeated measures ANOVAs of measurements from the circuit compared data from 12 to 48 h. Only INR differed overtime, with a significant difference between 12 and 48 h in post hoc comparisons (p = 0.002)

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