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Table 3 Comparison of the drugs administrated via PIVC with or without phlebitis

From: Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units

 

No. of catheters with drug administration

N = 3429

Proportion of phlebitis within drug (%)

Phlebitis ( +)

N = 313

Phlebitis (−)

N = 3116

P value

Fentanyl (n, %)

1463 (13.5%)

10.6

49 (15.7%)

414 (13.3%)

0.24

Heparin (n, %)

334 (9.7%)

8.4

28 (8.9%)

306 (9.8%)

0.62

Fat (n, %)

308 (9.0%)

11.4

35 (11.2%)

273 (8.8%)

0.15

Nicardipine (n, %)

307 (9.0%)

16.9

52 (16.6%)

255 (8.2%)

 < 0.0001

Dexmedetomidine (n, %)

292 (8.5%)

14.0

41 (13.1%)

251 (8.1%)

0.002

Ampicillin/sulbactam (n, %)

199 (5.8%)

10.1

20 (6.4%)

179 (5.7%)

0.64

Albumin (n,%)

176 (5.1%)

14.2

25 (8.0%)

151 (4.8%)

0.02

Paracetamol (n,%)

166 (4.8%)

6.0

10 (3.2%)

156 (5.0%)

0.16

Potassium (n, %)

154 (4.5%)

16.9

26 (8.3%)

128 (4.1%)

0.0006

Meropenem (n, %)

135 (3.9%)

11.9

16 (5.1%)

119 (3.8%)

0.26

Steroid (n, %)

125 (3.7%)

7.2

9 (2.9%)

116 (3.7%)

0.45

Ceftriaxone (n, %)

125 (3.7%)

10.4

13 (4.2%)

112 (3.6%)

0.62

Vancomycin (n, %)

120 (3.5%)

5.8

7 (2.2%)

113 (3.6%)

0.20

Magnesium (n, %)

111 (3.2%)

9.9

11 (3.4%)

100 (3.2%)

0.77

PPN (n, %)

92 (2.7%)

10.9

10 (3.2%)

82 (2.6%)

0.56

Phosphorus (n, %)

91 (2.7%)

13.2

12 (3.8%)

79 (2.5%)

0.17

Noradrenaline (n, %)

88 (2.6%)

21.6

19 (6.1%)

69 (2.2%)

 < 0.0001

Carperitide (n, %)

88 (2.6%)

13.6

12 (3.8%)

76 (2.4%)

0.14

Midazolam (n, %)

60 (1.8%)

20.0

12 (3.8%)

48 (1.5%)

0.003

Nitroglycerin (n, %)

60 (1.8%)

10.0

6 (1.9%)

54 (1.7%)

0.81

Dobutamine (n, %)

50 (1.5%)

14.0

7 (2.2%)

43 (1.4%)

0.23

Cefmetazole (n, %)

48 (1.4%)

8.3

4 (1.3%)

44 (1.4%)

0.85

Amiodarone (n, %)

41 (1.2%)

22.0

9 (2.9%)

32 (1.0%)

0.004

Cefepime (n, %)

41 (1.2%)

9.8

4 (1.3%)

37 (1.2%)

0.89

Levetiracetam (n, %)

41 (1.2%)

26.8

11 (3.5%)

30 (1.0%)

 < 0.0001

Landiolol (n, %)

40 (1.2%)

10.0

4 (1.3%)

36 (1.2%)

0.85

  1. PIVC peripheral intravenous catheter, PPN peripheral parenteral nutrition