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Table 3 Comparison of the drugs administrated via PIVC with or without phlebitis

From: Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units

  No. of catheters with drug administration
N = 3429
Proportion of phlebitis within drug (%) Phlebitis ( +)
N = 313
Phlebitis (−)
N = 3116
P value
Fentanyl (n, %) 1463 (13.5%) 10.6 49 (15.7%) 414 (13.3%) 0.24
Heparin (n, %) 334 (9.7%) 8.4 28 (8.9%) 306 (9.8%) 0.62
Fat (n, %) 308 (9.0%) 11.4 35 (11.2%) 273 (8.8%) 0.15
Nicardipine (n, %) 307 (9.0%) 16.9 52 (16.6%) 255 (8.2%)  < 0.0001
Dexmedetomidine (n, %) 292 (8.5%) 14.0 41 (13.1%) 251 (8.1%) 0.002
Ampicillin/sulbactam (n, %) 199 (5.8%) 10.1 20 (6.4%) 179 (5.7%) 0.64
Albumin (n,%) 176 (5.1%) 14.2 25 (8.0%) 151 (4.8%) 0.02
Paracetamol (n,%) 166 (4.8%) 6.0 10 (3.2%) 156 (5.0%) 0.16
Potassium (n, %) 154 (4.5%) 16.9 26 (8.3%) 128 (4.1%) 0.0006
Meropenem (n, %) 135 (3.9%) 11.9 16 (5.1%) 119 (3.8%) 0.26
Steroid (n, %) 125 (3.7%) 7.2 9 (2.9%) 116 (3.7%) 0.45
Ceftriaxone (n, %) 125 (3.7%) 10.4 13 (4.2%) 112 (3.6%) 0.62
Vancomycin (n, %) 120 (3.5%) 5.8 7 (2.2%) 113 (3.6%) 0.20
Magnesium (n, %) 111 (3.2%) 9.9 11 (3.4%) 100 (3.2%) 0.77
PPN (n, %) 92 (2.7%) 10.9 10 (3.2%) 82 (2.6%) 0.56
Phosphorus (n, %) 91 (2.7%) 13.2 12 (3.8%) 79 (2.5%) 0.17
Noradrenaline (n, %) 88 (2.6%) 21.6 19 (6.1%) 69 (2.2%)  < 0.0001
Carperitide (n, %) 88 (2.6%) 13.6 12 (3.8%) 76 (2.4%) 0.14
Midazolam (n, %) 60 (1.8%) 20.0 12 (3.8%) 48 (1.5%) 0.003
Nitroglycerin (n, %) 60 (1.8%) 10.0 6 (1.9%) 54 (1.7%) 0.81
Dobutamine (n, %) 50 (1.5%) 14.0 7 (2.2%) 43 (1.4%) 0.23
Cefmetazole (n, %) 48 (1.4%) 8.3 4 (1.3%) 44 (1.4%) 0.85
Amiodarone (n, %) 41 (1.2%) 22.0 9 (2.9%) 32 (1.0%) 0.004
Cefepime (n, %) 41 (1.2%) 9.8 4 (1.3%) 37 (1.2%) 0.89
Levetiracetam (n, %) 41 (1.2%) 26.8 11 (3.5%) 30 (1.0%)  < 0.0001
Landiolol (n, %) 40 (1.2%) 10.0 4 (1.3%) 36 (1.2%) 0.85
  1. PIVC peripheral intravenous catheter, PPN peripheral parenteral nutrition