Table 2 Pulmonary function test, 6-min walking test, and CT scan at 1-year follow-up
Variables | All patients | Non-severe patients | Severe patients | P value * |
|---|---|---|---|---|
Pulmonary function, N | 113 | 87 | 26 | |
FVC < 80% predicted, N (%) | 4 (3.5) | 2 (2.3) | 2 (7.7) | 0.483 |
FEV1 < 80% predicted, N (%) | 9 (8.0) | 7 (8.0) | 2 (7.7) | 1.000 |
FVC/FEV1 < 80% predicted, N (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | na |
MMEF < 65% predicted, N (%) | 36 (31.9) | 27 (31.0) | 9 (34.6) | 0.917 |
DLCO < 80%, predicted, N (%) | 40 (35.4) | 27 (31.0) | 13 (50.0) | 0.123 |
DLCO/VA < 80%, predicted, N (%) | 10 (8.8) | 5 (5.7) | 5 (19.2) | 0.084 |
TLC < 80%, predicted, N (%) | 9 (8.0) | 5 (5.7) | 4 (15.4) | 0.238 |
RV < 80% predicted, N (%) | 2 (1.8) | 2 (2.3) | 0 (0.0) | 1.000 |
6-min walking test, N | 187 | 146 | 41 | |
Distance < 450 m, N (%) | 86 (46.0) | 61 (41.8) | 25 (61.0) | 0.045 |
CT scan, N | 208 | 160 | 48 | |
Involvement of the lesions, N (%) | < 0.001 | |||
No involvement | 76 (36.5) | 69 (43.1) | 7 (14.6) | |
Single lobe | 56 (26.9) | 48 (30.0) | 8 (16.7) | |
Bilateral multilobe | 76 (36.5) | 43 (26.9) | 33 (68.8) | |
No. of lobes involved, median (IQR) | 1 (0 − 2) | 1 (0 − 2) | 2 (1 − 4) | < 0.001 |
Total CT score, mean (SD) | 2.29 (3.29) | 1.44 (2.05) | 5.15 (4.78) | < 0.001 |