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Annals of Intensive Care
Fig. 4 | Annals of Intensive Care

Fig. 4

From: Early antibiotic therapy is associated with a lower probability of successful liberation from mechanical ventilation in patients with severe acute exacerbation of chronic obstructive pulmonary disease

Fig. 4

Sensitivity analysis of the SHR of eABT in subgroups of patients assessed by modelling the probability of being successfully weaned from mechanical ventilation using multivariate competing risk regression. eABT was the first line of antibiotic therapy introduced during the first 24 h of ICU admission. Documented bacterial bronchitis was defined as bacterial documentation on respiratory sample performed between 48 h before ICU admission and the end of ICU day-1. Seventy-four Torr was the median value of ICU Day-1 worst PaCO2. SHR less than 1 indicates a lower probability of being successfully weaned from mechanical ventilation, accounting for the competing risk of death. SHR subdistribution hazard ratio, CI95% 95% confidence interval, eABT early antibiotic therapy, COPD chronic obstructive pulmonary disease, NIV non-invasive ventilation, ICU intensive care unit

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