Skip to main content

Table 4 Adverse events and clinical outcomes of prolonged continuous prone positioning

From: Continuous prolonged prone positioning in COVID-19-related ARDS: a multicenter cohort study from Chile

 

Total (n = 417)

Group A (n = 191)

Group B (n = 128)

Group C (n = 98)

p-value

Adverse events, n (%)

 Pressure soresa, n (%)

97 (23.9)

27 (14.2)

29 (23.6)

41 (44.1)

 < 0.001

 Pressure sores up to day 7b, n (%)

147 (36.2)

63 (33.2)

41 (33.3)

43 (46.2)

0.077

 Vascular catheters displacementa, n (%)

11 (2.7)

4 (2.1)

3 (2.4)

4 (4.3)

0.535

 Non-scheduled extubationa, n (%)

17 (4.2)

8 (4.2)

4 (3.3)

5 (5.4)

0.465

 Endotracheal obstructiona, n (%)

14 (3.4)

5 (2.6)

4 (3.3)

5 (5.4)

0.728

Clinical outcomes

 90-day mortality, n (%)

151 (36.2)

58 (30.4)

46 (35.9)

47 (48)

0.014

 ICU-mortality, n (%)

131 (31.4)

53 (27.8)

37 (28.9)

41 (41.8)

0.043

 In-hospital mortality, n (%)

139 (33.3)

54 (28.3)

39 (30.5)

46 (46.9)

0.005

 Tracheostomy, n (%)

80 (19.6)

20 (10.7)

24 (19)

36 (37.5)

 < 0.001

 Time on MV (days), median (IQR)

15 (10–22)

12 (8- 19)

16 (11–23)

21 (13–32)

 < 0.001

 ICU LoS (days), median (IQR)

17 (13–25)

15 (11–22)

18 (13–27)

22 (15–32)

 < 0.001

 Hospital LoS (days), median (IQR)

24 (16–38)

21 (14–33)

27 (16–40)

29 (16–50)

0.001

  1. aIncidence relate to the first prone session
  2. bCumulative incidence up to day 7 (considering  ≥ 1 prone session)
  3. Group A patients remained 2–3 days in prone position during their first session. Group B patients remained 4–5 days in prone position during their first session. Group C patients remained more than 5 days in prone position during their first session
  4. ICU intensive care unit; MV: mechanical ventilation; LoS: length of stay