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Table 3 Clinical characteristics at hospital admission of survivors and non survivors patients

From: Differences in clinical characteristics and quantitative lung CT features between vaccinated and not vaccinated hospitalized COVID-19 patients in Italy

 

Survivors

n = 537 (78.5%)

Non survivors

n = 147 (21.5%)

p

Demographic characteristics

Age, years

64 [52–76]

81 [74–86]

 < 0.001

Male gender, n (%)

314 (58.5)

84 (57.1)

0.772

Caucasian, n (%)

459 (85.5)

141 (95.9)

0.012

Latin/hispanic n (%)

24 (4.5)

0 (0.0)

Other, n (%)

54 (10.0)

6 (4.1)

Underlying comorbidities

Hypertension, n (%)

217 (40.4)

83 (56.5)

0.001

Stroke, n (%)

17 (3.2)

16 (10.9)

 < 0.001

AMI, n (%)

42 (7.8)

28 (19.0)

 < 0.001

Diabetes, n (%)

100 (18.6)

33 (22.4)

0.299

Cardiovascular diseases, n (%)

88 (16.4)

47 (32.0)

 < 0.001

COPD, n (%)

39 (7.3)

25 (17.0)

 < 0.001

History of cancer, n (%)

32 (6.0)

26 (17.7)

 < 0.001

CKD, n (%)

27 (5.0)

21 (14.3)

 < 0.001

Chronic liver disease, n (%)

13 (2.4)

2 (1.34

0.437

Age-adjusted Charlson score

2 (1–4)

5 (4–6)

 < 0.001

Laboratory data

Haemoglobin, g/dL

13.7 [12.2–14.8]

12.8 [11.1–14.3]

0.009

CRP, mg/L

50.5 [24.9–81.9]

62.1 [38.0–102.7]

0.001

LDH, U/L

287 [232–372]

307 [256–411]

0.035

Leukocytes count, 103/µL

6.16 [4.60–8.41]

6.70 [4.28–10.18]

0.143

Platelets,103/µL

186 [147–242]

191 [134–252]

0.863

D-Dimer, ng/mL

274 [192–553]

476 [289–854]

 < 0.001

GPT, U/L

30 [21–53]

23 [17–39]

 < 0.001

GOT, U/L

42 [32–61]

47 [36–63]

0.246

Creatinine, mg/dL

0.9 [0.7–1.1]

1.1 (0.8–1.5)

 < 0.001

Procalcitonin, µg/L

0.14 [0.05–0.84]

0.20 (0.11–0.57)

0.273

Ferritin, ng/mL

321 [189–634]

469 [117–991]

0.428

Pharmacological treatments

Remdesivir, n (%)

148 (27.6)

26 (17.7)

0.015

Heparin profilaxis, n (%)

446 (83.0)

116 (78.9)

0.245

Corticosteroid treatment, n (%)

447 (83.2)

130 (88.4)

0.124

Biological immunomodulator, n (%)

38 (7.1)

12 (8.2)

0.654

Monoclonal antibodies, n (%)

50 (7.3)

22 (3.8)

0.180

  1. Continuous variables are expressed as median [IQR] and compared with Mann–Whitney U test, while categorical data are expressed as n (%) and compared with Chi-square test
  2. COPD chronic obstructive pulmonary disease, AMI  acute myocardial infarction, CKD  chronic kidney disease, CRP  C-reactive protein, LDH  lactate dehydrogenase, GOT  glutamic–oxalacetic transaminase, GPT  glutamate–pyruvate transaminase. History of cancer was defined as a cancer diagnosis in the last 5 years