Differences in clinical characteristics and quantitative lung CT features between vaccinated and not vaccinated hospitalized COVID-19 patients in Italy

Annals of Intensive Care

Table 4 Respiratory function and lung CT scan quantitative data at hospital admission in survivors and non survivors patients

	Survivors n = 537 (78.5%)	Non survivors n = 147 (21.5%)	p
Respiratory function
Respiratory rate, breaths/min	20 [17–25]	23 [20–56]	0.115
PaO₂/FiO₂	309.5 [266.7–347.6]	255.7 [185.7–323.8]	< 0.001
PaO₂, mmHg	69.0 [61.0–80.4]	68.7 [56.9–84.0]	0.355
PaCO₂, mmHg	33.5 [30.5–36.7]	32.0 [29.5–36.0]	0.015
Lung CT scan quantitative data
Total gas volume, ml	2476 [1733–3425]	2023 [1435–2623]	< 0.001
Total lung weight, g	938 [792–1121]	991 [810–1202]	0.064
Over aerated lung weight, %	2.2 [0.6–5.8]	1.5 [0.6–4.2]	< 0.020
Normally aerated lung weight, %	61.9 [53.8–68.3]	51.8 [41.4–62.0]	< 0.001
Poorly aerated lung weight, %	23.7 [18.1–30.3]	30.5 [23–39.3]	< 0.001
Not aerated lung weight, %	8.4 [6–12.8]	11.5 [7.1–18.5]	< 0.001

Continuous variables are expressed as median [IQR] and compared with Mann–Whitney U test
FiO₂ inspired fraction of O₂, PaO₂ arterial partial pressure of O₂, PaCO₂ arterial partial pressure of CO₂