Table 1 Baseline characteristics of patients
Early strategy (N = 53) | Delayed strategy (N = 59) | |
|---|---|---|
Sex–N, % male | 41 (77.4) | 35 (59.3) |
Age–year | 67 [55–73] | 66 [58–76] |
Underlying disease, N (%) | ||
- Chronic kidney diseasea | 3 (5.7) | 4 (6.8) |
- Chronic arterial hypertension | 29 (54.7) | 29 (49.2) |
- Congestive heart failure | 6 (11.3) | 4 (6.8) |
- Ischemic heart disease | 6 (11.3) | 5 (8.5) |
- Chronic liver disease | 1 (1.9) | 1 (1.7) |
- Diabetes mellitus | 15 (28) | 10 (17) |
- Malignant disease | 10 (18.9) | 14 (23.7) |
- Neutropenia | 1 (1.9) | 3 (5.1) |
SAPS IIIb at enrollment | 61 [55–73] | 67 [58–74] |
SOFAc score at enrollment | 11 [9–13] | 10 [8–13] |
Physiological support, N (%) | ||
- Invasive mechanical ventilation | 48 (90.6) | 52 (88.1) |
- Vasopressors | 44 (83.0) | 53 (89.8) |
Sepsis status, N (%) | ||
- Septic shock | 38 (71.7) | 45 (76.3) |
- Severe sepsis | 2 (3.8) | 5 (8.5) |
- Sepsis | 2 (3.8) | 4 (6.8) |
- No sepsis | 11 (20.8) | 5 (8.5) |
Serum creatinine, µM | 192 ± 137 | 186 ± 120 |
Serum urea, mM | 12.9 ± 9.1 | 14.4 ± 9.8 |
Patients with oliguria or anuria, N (%) | 31 (59.6) | 25 (43.9) |