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Table 2 Population outcomes

From: Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial

 

Treatment group

(n = 15)

Placebo group

(n = 6)

p

During ICU stay:

 - Vasopressor support, (day)a

 - Mechanical ventilation, (day)a

 - Renal replacement therapy, (n)

0 (0, 2)

8 (5, 12)

6

0 (0, 7)

7 (0, 14)

3

0.83

0.54

1

Organ support free days (day)a

19 (12, 29)

8 (3, 11)

 < 0.05

Secondary infection, (n(%))

8 (53.3%)

2 (33.3%)

0.64

Site of secondary infection (n = 10 (%)):

 - Pulmonary

 - Bloodstream

 - Otherb

4 (40.0%)

1 (10.0%)

3 (30.0%)

1 (10.0%)

1 (10.0%)

0

 

Length of ICU stay, including ICU readmission (day)*

16 (9, 32)

14 (9, 19)

0.54

Antibiotic consumption at day 29 or hospital discharge, (day)a

20 (4, 29)

13 (11, 16)

 < 0.05

Mortality at day 90, (n(%))

3 (20.0%)

2 (33.3%)

0.48

  1. aValues reported are median (interquartile range). Dead patients are counted as 0 organ support free days alive
  2. b Skin, intra-abdominal, osteitis