Treatment group (n = 15) | Placebo group (n = 6) | p | |
---|---|---|---|
During ICU stay: - Vasopressor support, (day)a - Mechanical ventilation, (day)a - Renal replacement therapy, (n) | 0 (0, 2) 8 (5, 12) 6 | 0 (0, 7) 7 (0, 14) 3 | 0.83 0.54 1 |
Organ support free days (day)a | 19 (12, 29) | 8 (3, 11) | < 0.05 |
Secondary infection, (n(%)) | 8 (53.3%) | 2 (33.3%) | 0.64 |
Site of secondary infection (n = 10 (%)): - Pulmonary - Bloodstream - Otherb | 4 (40.0%) 1 (10.0%) 3 (30.0%) | 1 (10.0%) 1 (10.0%) 0 | |
Length of ICU stay, including ICU readmission (day)* | 16 (9, 32) | 14 (9, 19) | 0.54 |
Antibiotic consumption at day 29 or hospital discharge, (day)a | 20 (4, 29) | 13 (11, 16) | < 0.05 |
Mortality at day 90, (n(%)) | 3 (20.0%) | 2 (33.3%) | 0.48 |