Skip to main content
Annals of Intensive Care

Table 4 Outcomes according to the obesity status

From: Preoxygenation with standard facemask combining apnoeic oxygenation using high flow nasal cannula versuss standard facemask alone in patients with and without obesity: the OPTIMASK international study

 

Patients without obesity

Facemask alone (n = 185)

Facemask combined with HFNO (n = 172)

p value

Patients with obesity

Facemask alone (n = 48)

Facemask combined with HFNO (n = 45)

p value

Overall (n = 357)

Overall (n = 93)

Primary: lowest EtO2 within 2 min after intubation (%)a

90 (88–93)

90 (86–92)

91 (89–93)

0.001

89 (85–91)

87 (82–91)

90 (88–92)

0.004

Secondary:

 SpO2 at the end of preoxygenation (%)

100 (100–100)

100 (100–100)

100 (100–100)

0.18

100 (100–100)

100 (100–100)

100 (100–100)

0.28

 First EtO2 after intubation (%)b

91 (88–100)

91 (87–100)

92 (89–99)

0.05

90 (86–92)

89 (86–92)

90 (89–94)

0.01

 Highest EtCO2 after intubation (%)b

37 (34–41)

37 (34–40)

37 (33–41)

0.28

37 (34–40)

37 (34–40)

36 (34–39)

0.68

 Lowest EtCO2 within 2 min after intubation (%)c

35 (32–38)

35 (32–38)

35 (33–39)

0.60

36 (32–38)

36 (32–39)

35 (32–37)

0.34

 First SpO2 after intubation (%)d

100 (100–100)

100 (100–100)

100 (100–100)

0.43

100 (99–100)

100 (99–100)

100 (99–100)

0.76

 Lowest SpO2 during intubation and within 2 min after intubation (%)d

100 (99–100)

100 (100–100)

100 (99–100)

0.52

100 (98–100)

100 (98–100)

100 (98–100)

0.76

 SpO2 ≤ 95% during intubation and within 2 min after intubation

7/356 (2.0)

6/185 (3.2)

1/171 (0.58)

0.12

9/91 (9.9)

8/47 (17.0)

1/44 (2.3)

0.03

 Ease of use of preoxygenation (from 0 to 10)e

9 (8–10)

10 (9–10)

8 (7–9)

 < 0.001

9 (7–10)

10 (9–10)

8 (6–9)

 < 0.001

 First-attempt success

333/352 (94.6)

169/181 (93.4)

164/171 (95.9)

0.29

83/89 (93.3)

41/44 (93.2)

42/45 (93.3)

1.00

 Excellent conditions of intubation

202/326 (62.0)

103/169 (60.9)

99/157 (63.1)

0.69

51/80 (63.8)

24/40 (60.0)

27/40 (67.5)

0.49

  1. Data are n/N (%), and median (IQR)
  2. SpO2 Peripheral oxygen saturation, EtO2 end-tidal oxygen, EtCO2 end-tidal carbon dioxide, HFNO High-Flow Nasal cannula Oxygen
  3. aData on lowest EtO2 after intubation were missing for 1 patients (1.0%) in patients with obesity and 1 (0.3%) in patients without obesity
  4. bData on first EtO2 after intubation were missing for 2 patients (2.2%) in patients with obesity and 11 (3.1%) in patients without obesity
  5. cData on highest and lowest EtCO2 after intubation were missing for 1 patients (1.0%) in patients with obesity and 1 (0.3%) in patients without obesity
  6. dData on first and lowest SpO2 after intubation were missing for 1 patients (1.0%) in patients with obesity and 1 (0.3%) in patients without obesity
  7. eData on ease of use of preoxygenation were missing for 40 patients (43.0%) in patients with obesity and 82 (23.0%) in patients without obesity
Back to article page